2. Gene
  3. LDHB - lactate dehydrogenase B Gene

LDHB - lactate dehydrogenase B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 281275 | Gene type: protein coding

About LDHB

Summary

This gene encodes the B subunit of Lactate Dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Recent studies have shown that two protein isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism, and that these C-terminally distinct isoforms have different subcellular localization. Pseudogenes have been identified on chromosomes 1 and 11. [provided by RefSeq, Oct 2015]

LDHB Products(2)

mRNA Protein Name
NM_001316338.1 NP_001303267.1 L-lactate dehydrogenase B chain isoform LDHBx
NM_174100.2 NP_776525.2 L-lactate dehydrogenase B chain isoform LDHB
Protein Preferred Names Protein Names

L-lactate dehydrogenase B chain

LDH-B

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-147216 AXKO-0046 Inhibitor 99.77% Unkown
HY-118241 GNE-140 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens LDHB NCBI NCBI:3945