TGFB1 - transforming growth factor beta 1 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 282089

About TGFB1

Primary_assembly 18: 50,484,512-50,508,692 reverse strand.ARS-UCD1.2:CM008185.2

This gene has 4 transcripts (splice variants), 211 orthologues and 32 paralogues.

TGFB1 Products (1)

mRNA Protein Name
NM_001166068.1 NP_001159540.1 transforming growth factor beta-1 proprotein precursor

TGFB1 Protein Structure

TGFb_propeptide

TGFb_propeptide: pfam00688 (29 - 261)

TGF_beta_SF

TGF_beta_SF: cl40434 (292 - 338)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500 a.a.
Protein Preferred Names Protein Names

transforming growth factor beta-1 proprotein

transforming growth factor beta-1

  • TGF-beta-1

  • transforming growth factor, beta 1 (Camurati-Engelmann disease)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99305 Metelimumab Inhibitor 98.98% Phase 2
HY-P991382 SAR-439459 Inhibitor / Phase 2
HY-P991383 LY2382770 Inhibitor / Phase 2
HY-P991950 SHR-1906 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14435 TGFB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W764758 3-OH-Kynurenamine dihydroiodide Activator 99.56% Unkown
HY-RS14436 Tgfb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-147195 QH536 Inhibitor / Unkown
HY-156908 3-OH-Kynurenamine Activator / Unkown
HY-RS14437 Tgfb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14438 TGFB1I1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174534 Human TGFB1 mRNA / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99606 Cirevetmab Inhibitor ≥99.0% Unkown
HY-P990517 Anti-TGFb1 Antibody Inhibitor 98.24% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TGFB1 NCBI NCBI:7040