SLC26A11 - solute carrier family 26 member 11 Gene

Homo sapiens

Gene ID: 284129 | Gene type: protein coding

About SLC26A11

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:80,220,427-80,253,500 (from NCBI)

This gene has 17 transcripts (splice variants), 213 orthologues and 9 paralogues. Ubiquitous expression in adrenal (RPKM 8.3), spleen (RPKM 6.4) and 25 other tissues.

Summary

This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

SLC26A11 Products(4)

mRNA	Protein	Name
NM_001166347.2	NP_001159819.1	sodium-independent sulfate anion transporter
NM_001166348.2	NP_001159820.1	sodium-independent sulfate anion transporter
NM_001166349.2	NP_001159821.1	sodium-independent sulfate anion transporter
NM_173626.4	NP_775897.3	sodium-independent sulfate anion transporter

SLC26A11 Protein Structure

Sulfate_transp

STAS

0
100
200
300
400
500
606 a.a.

Protein Preferred Names

Protein Names

sodium-independent sulfate anion transporter

solute carrier family 26 (anion exchanger), member 11

Related Diseases

Diseases

Alias

Sialolithiasis

Sialolith	Stone Of Salivary Gland Or Duct
Salivary Gland Calculi	Salivary Gland Stone
Calculus Of Salivary Gland Or Duct	Calculus Of Salivary Gland
Salivary Calculus	Salivary Gland Calculus
Salivary Stone	Salivary Duct Calculi
Sialodocholithiasis

Pendred Syndrome

Goiter-Deafness Syndrome	Deafness With Goiter
PDS	Thyroid Dyshormonogenesis 2b
Tdh2b	Autosomal Recessive Sensorineural Hearing Impairment And Goiter
Pendred'S Syndrome	Thyroid Hormonogenesis, Genetic Defect In, 2b
Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b	Congenital Hypothyroidism Due To Dyshormonogenesis 2b
Genetic Defect In Thyroid Hormonogenesis 2b	Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter
Goiter-Hearing Loss Syndrome	Goitre-Deafness Syndrome
Goitre Deafness

Moyamoya Disease 1

Moyamoya Disease	Spontaneous Occlusion Of The Circle Of Willis
Mymy	Progressive Intracranial Arterial Occlusion
Moyamoya Syndrome	MYMY1
Cerebrovascular Moyamoya Disease	Moya-Moya Disease
Progressive Intracranial Occlusive Arteropathy	Idiopathic Moyamoya Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13135	SLC26A11 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SLC26A11	MGD	MGI:2444589
Felis catus	SLC26A11	VGNC	VGNC:65282
Canis familiaris	SLC26A11	VGNC	VGNC:46321
Bos taurus	SLC26A11	VGNC	VGNC:34776
Macaca mulatta	SLC26A11	VGNC	VGNC:77482
Rattus norvegicus	SLC26A11	RGD	RGD:1306178

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