Ric8a - RIC8 guanine nucleotide exchange factor A Gene

Also Known as Ric8; Ric-8A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293614

Summary

Enables G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Located in cytoplasm and plasma membrane. Orthologous to human RIC8A (RIC8 guanine nucleotide exchange factor A). [provided by Alliance of Genome Resources, Apr 2022]

Ric8a Products (1)

mRNA Protein Name
NM_001100520.1 NP_001093990.1 synembryn-A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G-protein alpha-subunit binding IDA
IDA: Inferred from direct assay
12509430 RGD
enables G-protein alpha-subunit binding IPI
IPI: Inferred from physical interaction
12509430 RGD
enables GTPase activator activity IDA
IDA: Inferred from direct assay
12509430 RGD
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
12509430 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
21158412 RGD
enables protein folding chaperone IDA
IDA: Inferred from direct assay
31155309 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
31155309 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21158412 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
21158412 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synembryn-A

  • heterotrimeric G protein guanine nucleotide exchange factor Ric-8A

  • resistance to inhibitors of cholinesterase 8 homolog

  • resistance to inhibitors of cholinesterase 8A

  • resistance to inhibitors of cholinesterase 8A-like protein

  • synembryn

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122579 IGS-1.76 Inhibitor 98.57% Unkown
HY-RS11967 RIC8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-121503 FD44 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ric8a NCBI NCBI:60626