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IGS-1.76 

Cat. No.: HY-122579 Purity: 98.56%
Handling Instructions

IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.

For research use only. We do not sell to patients.

IGS-1.76 Chemical Structure

IGS-1.76 Chemical Structure

CAS No. : 313480-47-6

Size Price Stock Quantity
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 500 In-stock
Estimated Time of Arrival: December 31
25 mg USD 950 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2350 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1].

In Vitro

IGS-1.76 is a Drosophila NCS-1/IGS-1.76 complex inhibitor[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

358.46

Formula

C₂₂H₁₈N₂OS

CAS No.

313480-47-6

SMILES

O=C(NC1=NC2=CC=CC=C2S1)CC(C3=CC=CC=C3)C4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (697.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7897 mL 13.9486 mL 27.8971 mL
5 mM 0.5579 mL 2.7897 mL 5.5794 mL
10 mM 0.2790 mL 1.3949 mL 2.7897 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.80 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

IGS-1.76OthersPPINCS-1Ric8aInhibitorinhibitorinhibit

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Product Name:
IGS-1.76
Cat. No.:
HY-122579
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