Gjb3 - gap junction protein, beta 3 Gene

Also Known as Cxnc

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29585

Summary

Predicted to enable gap junction channel activity. Involved in several processes, including cellular response to retinoic acid; skin development; and spermatogenesis. Located in gap junction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2B; autosomal recessive nonsyndromic deafness 1A; erythrokeratodermia variabilis; and erythrokeratodermia variabilis et progressiva 1. Orthologous to human GJB3 (Gap Junction Protein beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Gjb3 Products (2)

mRNA Protein Name
NM_001411660.1 NP_001398589.1 gap junction beta-3 protein
NM_019240.2 NP_062113.1 gap junction beta-3 protein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
8806447 RGD
involved in in utero embryonic development IEP
IEP: Inferred from expression pattern
9291584 RGD
involved in skin development IEP
IEP: Inferred from expression pattern
8081010 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
10405153 RGD
Cellular Component GO Annotation Evidence References Source
located in gap junction IDA
IDA: Inferred from direct assay
12123633 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-3 protein

  • connexin c

  • connexin-31

  • cx31

  • gap junction membrane channel protein beta 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05448 GJB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22183 Gjb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28705 Gjb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb3 NCBI NCBI:2707