2. Gene
  3. SLC2A8 - solute carrier family 2 member 8 Gene

SLC2A8 - solute carrier family 2 member 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GLUT8; GLUTX1

Gene ID: 29988 | Gene type: protein coding

About SLC2A8

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:127,397,169-127,407,898 (from NCBI)

This gene has 15 transcripts (splice variants), 261 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.3), adrenal (RPKM 7.3) and 24 other tissues.

Summary

This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

SLC2A8 Products(3)

mRNA Protein Name
NM_001271711.2 NP_001258640.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 2
NM_001271712.2 NP_001258641.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 3
NM_014580.5 NP_055395.2 solute carrier family 2, facilitated glucose transporter member 8 isoform 1

SLC2A8 Protein Structure

Sugar_tr

Sugar_tr: Sugar (and other) transporter (30 - 473)

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  • 400
  • 477 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 8

glucose transporter type 8

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 10

Diabetes Mellitus, Insulin-Dependent, 10

IDDM10

Insulin-Dependent Diabetes Mellitus 10

Diabetes, Mellitus, Insulin-Dependent, Susceptibility To, 10

T1D10

Diabetes, Mellitus, Insulin-Dependent 10

Diabetes Mellitus, Insulin-Dependent, Type 10
Arterial Tortuosity Syndrome

Arterial Tortuosity

Ats

ATORS

Tortuosity, Arterial, Syndrome
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139047 SW157765 Inhibitor 98.67% Unkown
HY-RS13176 SLC2A8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC2A8 VGNC VGNC:34803
Rattus norvegicus SLC2A8 RGD RGD:620611
Mus musculus SLC2A8 MGD MGI:1860103
Felis catus SLC2A8 VGNC VGNC:65306
Canis familiaris SLC2A8 VGNC VGNC:46344
Macaca mulatta SLC2A8 VGNC VGNC:77470