SLC2A8 - solute carrier family 2 member 8 Gene

Also Known as GLUT8; GLUTX1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29988

About SLC2A8

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:127,397,169-127,407,898 (from NCBI)

This gene has 15 transcripts (splice variants), 261 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.3), adrenal (RPKM 7.3) and 24 other tissues.

Summary

This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like Other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

SLC2A8 Products (3)

mRNA Protein Name
NM_001271711.2 NP_001258640.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 2
NM_001271712.2 NP_001258641.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 3
NM_014580.5 NP_055395.2 solute carrier family 2, facilitated glucose transporter member 8 isoform 1

SLC2A8 Protein Structure

Sugar_tr

Sugar_tr: Sugar (and other) transporter (30 - 473)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 477 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 8

  • glucose transporter type 8

SLC2A8 Antibodies

Cat. No. Product Name Application Reactivity
HY-P811360 GLUT8/ DA41 Antibody WB, IHC-P, FC Human, Mouse, Rat

Related Diseases

Diseases Alias
Type 1 Diabetes Mellitus 10

  • Diabetes Mellitus, Insulin-Dependent, 10

  • IDDM10

  • Insulin-Dependent Diabetes Mellitus 10

  • Diabetes, Mellitus, Insulin-Dependent, Susceptibility To, 10

  • T1D10

  • Diabetes, Mellitus, Insulin-Dependent 10

  • Diabetes Mellitus, Insulin-Dependent, Type 10
Arterial Tortuosity Syndrome

  • Arterial Tortuosity

  • Ats

  • ATORS

  • Tortuosity, Arterial, Syndrome
Hypoascorbemia

  • Scurvy

  • Ascorbic Acid Deficiency

  • Vitamin C Deficiency

  • Vitamin C, Inability To Synthesize

  • Deficiency Of Vitamin C

  • Scorbutus

  • Vitamin C
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139047 SW157765 Inhibitor 98.08% Unkown
HY-RS13176 SLC2A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990674 VB1-050 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC2A8 VGNC VGNC:34803
Rattus norvegicus SLC2A8 RGD RGD:620611
Mus musculus SLC2A8 MGD MGI:1860103
Felis catus SLC2A8 VGNC VGNC:65306
Canis familiaris SLC2A8 VGNC VGNC:46344
Macaca mulatta SLC2A8 VGNC VGNC:77470