2. Gene
  3. Mgrn1 - mahogunin ring finger 1 Gene

Mgrn1 - mahogunin ring finger 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1311862

Gene ID: 302938 | Gene type: protein coding

About Mgrn1

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in endosome to lysosome transport; negative regulation of signal transduction; and protein monoubiquitination. Predicted to act upstream of or within protein polyubiquitination. Predicted to be located in endoplasmic reticulum. Predicted to be active in early endosome; nucleus; and plasma membrane. Orthologous to human MGRN1 (mahogunin ring finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Mgrn1 Products(1)

mRNA Protein Name
NM_001013964.1 NP_001013986.1 E3 ubiquitin-protein ligase MGRN1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24036454 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase MGRN1

RING-type E3 ubiquitin transferase MGRN1

mahoganoid

mahogunin RING finger protein 1

mahogunin ring finger 1, E3 ubiquitin protein ligase

probable E3 ubiquitin-protein ligase MGRN1

Mgrn1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Mgrn1 Q5XIQ4 GDU1 Arabidopsis thaliana O81775
Y2H
24036454
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08415 MGRN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgrn1 NCBI NCBI:23295