Arhgap27 - Rho GTPase activating protein 27 Gene

Rattus norvegicus

Also known as CAMGAP1; Arhgap15

Gene ID: 303583 | Gene type: protein coding

About Arhgap27

Summary

Enables GTPase activator activity and SH3 domain binding activity. Involved in positive regulation of GTPase activity. Acts upstream of or within receptor-mediated endocytosis. Located in endosome. Orthologous to human ARHGAP27 (Rho GTPase activating protein 27). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap27 Products(1)

mRNA	Protein	Name
NM_198759.2	NP_942054.2	rho GTPase-activating protein 27

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activator activity	IDA IDA: Inferred from direct assay	15147912	RGD
enables SH3 domain binding	IDA IDA: Inferred from direct assay	15147912	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	15147912	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in Rho protein signal transduction	IDA IDA: Inferred from direct assay	15147912	RGD
acts upstream of or within receptor-mediated endocytosis	IDA IDA: Inferred from direct assay	15147912	RGD
involved in receptor-mediated endocytosis	IMP IMP: Inferred from mutant phenotype	15147912	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in endosome	IDA IDA: Inferred from direct assay	15147912	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

rho GTPase-activating protein 27

CIN85-associated multi-domain containing RhoGAP 1	CIN85-associated multi-domain-containing Rho GTPase-activating protein 1
Rho GTPase activating protein 15	rho-type GTPase-activating protein 27

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00927	ARHGAP27 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arhgap27	NCBI	NCBI:201176

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