ARHGAP27 - Rho GTPase activating protein 27 Gene
Also Known as PP905; SH3D20; SH3P20; CAMGAP1
Species: Homo sapiens
About ARHGAP27
This gene has 24 transcripts (splice variants), 1 gene allele, 276 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 12.5), spleen (RPKM 12.5) and 23 other tissues.
Summary
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing Enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]
ARHGAP27 Products (19)
| mRNA | Protein | Name |
|---|---|---|
| NM_001282290.2 | NP_001269219.1 | rho GTPase-activating protein 27 isoform d |
| NM_001385384.1 | NP_001372313.1 | rho GTPase-activating protein 27 isoform e |
| NM_001385385.1 | NP_001372314.1 | rho GTPase-activating protein 27 isoform f |
| NM_001385386.1 | NP_001372315.1 | rho GTPase-activating protein 27 isoform g |
| NM_001385387.1 | NP_001372316.1 | rho GTPase-activating protein 27 isoform h |
| NM_001385388.1 | NP_001372317.1 | rho GTPase-activating protein 27 isoform i |
| NM_001385389.1 | NP_001372318.1 | rho GTPase-activating protein 27 isoform j |
| NM_001385390.1 | NP_001372319.1 | rho GTPase-activating protein 27 isoform k |
| NM_001385391.1 | NP_001372320.1 | rho GTPase-activating protein 27 isoform l |
| NM_001385392.1 | NP_001372321.1 | rho GTPase-activating protein 27 isoform m |
| NM_001385393.1 | NP_001372322.1 | rho GTPase-activating protein 27 isoform n |
| NM_001385394.1 | NP_001372323.1 | rho GTPase-activating protein 27 isoform o |
| NM_001385395.1 | NP_001372324.1 | rho GTPase-activating protein 27 isoform p |
| NM_001385396.1 | NP_001372325.1 | rho GTPase-activating protein 27 isoform q |
| NM_001385397.1 | NP_001372326.1 | rho GTPase-activating protein 27 isoform r |
| NM_001385398.1 | NP_001372327.1 | rho GTPase-activating protein 27 isoform s |
| NM_001385399.1 | NP_001372328.1 | rho GTPase-activating protein 27 isoform s |
| NM_174919.4 | NP_777579.2 | rho GTPase-activating protein 27 isoform c |
| NM_199282.3 | NP_954976.1 | rho GTPase-activating protein 27 isoform a |
ARHGAP27 Protein Structure
WW: WW domain (247 - 278)
PH: PH domain (499 - 609)
RhoGAP: RhoGAP domain (711 - 860)
- 0
- 200
- 400
- 600
- 800
- 889 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
rho GTPase-activating protein 27 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Kanzaki Disease |
|
|
| Schindler Disease |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00927 | ARHGAP27 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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