2. Gene
  3. Map3k20 - mitogen-activated protein kinase kinase kinase 20 Gene

Map3k20 - mitogen-activated protein kinase kinase kinase 20 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Zak; MLTK; RGD1561394

Gene ID: 311743 | Gene type: protein coding

About Map3k20

Summary

Predicted to enable ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including cellular response to gamma radiation; intracellular signal transduction; and positive regulation of mitotic DNA damage checkpoint. Predicted to act upstream of or within Cytoskeleton organization and embryonic digit morphogenesis. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Orthologous to human MAP3K20 (mitogen-activated protein kinase kinase kinase 20). [provided by Alliance of Genome Resources, Apr 2022]

Map3k20 Products(4)

mRNA Protein Name
NM_001398993.1 NP_001385922.1 mitogen-activated protein kinase kinase kinase MLT isoform 1
NM_001398994.1 NP_001385923.1 mitogen-activated protein kinase kinase kinase MLT isoform 2
NM_001398993.1 NP_001385922.1 mitogen-activated protein kinase kinase kinase MLT isoform 1
NM_001398994.1 NP_001385923.1 mitogen-activated protein kinase kinase kinase MLT isoform 2
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase MLT

mitogen-activated protein kinase kinase kinase 20

sterile alpha motif and leucine zipper containing kinase AZK

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 96.07% Unkown
HY-RS08055 MAP3K20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k20 NCBI NCBI:51776