Lingo1 - leucine rich repeat and Ig domain containing 1 Gene

Rattus norvegicus

Also known as Lrrn6a

Gene ID: 315691 | Gene type: protein coding

About Lingo1

Summary

Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within generation of neurons and protein kinase B signaling. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and glaucoma. Orthologous to human LINGO1 (leucine rich repeat and Ig domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lingo1 Products(1)

mRNA	Protein	Name
NM_001100722.1	NP_001094192.1	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 precursor

Protein Preferred Names

Protein Names

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

leucine rich repeat neuronal 6A

Related Agents

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99780	Opicinumab	Antagonist	99.50%	Phase 2

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07680	LINGO1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lingo1	NCBI	NCBI:84894

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