country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

TMEM240 - transmembrane protein 240 Gene

Also Known as SCA21; C1orf70

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 339453

About TMEM240

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,534,778-1,540,624 (from NCBI)

This gene has 3 transcripts (splice variants), 211 orthologues and is associated with 3 phenotypes. Biased expression in brain (RPKM 2.8), endometrium (RPKM 1.2) and 13 other tissues.

Summary

This gene encodes a transmembrane-domain containing protein found in the brain and cerebellum. Mutations in this gene result in spinocerebellar ataxia 21. [provided by RefSeq, Dec 2014]

TMEM240 Products (1)

mRNA	Protein	Name
NM_001114748.2	NP_001108220.1	transmembrane protein 240

TMEM240 Protein Structure

TMEM240

0
100
173 a.a.

Protein Preferred Names	Protein Names
transmembrane protein 240	transmembrane protein C1orf70

Related Diseases

Diseases	Alias
Spinocerebellar Ataxia 21	Spinocerebellar Ataxia Type 21 SCA21 Ataxia, Spinocerebellar, Type 21
Cerebellar Ataxia Type 43	Sca43
Spinocerebellar Ataxia, Autosomal Recessive 21	SCAR21 Acute Infantile Liver Failure-Cerebellar Ataxia-Peripheral Sensory Motor Neuropathy Syndrome Spinocerebellar Ataxia, Autosomal Recessive 21, With Hepatopathy Cholestasis, Low Ggt, Acute Liver Failure, And Neurodegeneration Syndrome Calfan Autosomal Recessive Spinocerebellar Ataxia 21 Autosomal Recessive Spinocerebellar Ataxia 21 With Hepatopathy Autosomal Recessive Spinocerebellar Ataxia Type 21 Spinocerebellar Ataxia, Autosomal Recessive, 21 Calfan Syndrome
Cerebellar Ataxia Type 47	Sca47
Cerebellar Ataxia Type 48	Sca48
Spinocerebellar Ataxia 25	Spinocerebellar Ataxia Type 25 SCA25
Hereditary Ataxia	Sca Spinocerebellar Ataxia Ataxias Hereditary Ataxias, Hereditary
Spinocerebellar Ataxia, X-Linked 1	X-Linked Progressive Cerebellar Ataxia SCAX1 Opcax X-Linked Spinocerebellar Ataxia 1 Olivopontocerebellar Atrophy, X-Linked Opca, X-Linked Olivopontocerebellar Atrophy X-Linked Opca X-Linked Ataxia, Spinocerebellar, X-Linked Type 1
Boucher-Neuhauser Syndrome	Ataxia-Hypogonadism-Choroidal Dystrophy Syndrome BNHS Spinocerebellar Ataxia, Hypogonadotropic Hypogonadism, And Chorioretinal Dystrophy Boucher-Neuhäuser Syndrome Chorioretinal Dystrophy, Spinocerebellar Ataxia, And Hypogonadotropic Hypogonadism Ataxia - Hypogonadism - Choroidal Dystrophy Chorioretinal Dystrophy, Spinocerebellar Ataxia And Hypogonadotropic Hypogonadism Bns Cerebellar Ataxia With Hypogonadism And Choroidal Dystrophy Syndrome Boucher Neuhauser Syndrome
Spinocerebellar Ataxia 23	Spinocerebellar Ataxia Type 23 SCA23 Ataxia, Spinocerebellar, Type 23
Cerebellar Ataxia Type 41	Sca41
Spinocerebellar Ataxia, Autosomal Recessive 27	SCAR27 Autosomal Recessive Spinocerebellar Ataxia 27 Spinocerebellar Ataxia, Autosomal Recessive, 27
Spinocerebellar Ataxia 20	Spinocerebellar Ataxia Type 20 SCA20 Spinocerebellar Ataxia With Dysphonia Spinocerebellar Ataxia With Spasmodic Cough Chromosome 11q12 Duplication Syndrome, 260-Kb Chromosome 11q12 Duplication Syndrome 260-Kb
Spinocerebellar Ataxia 14	Spinocerebellar Ataxia Type 14 SCA14 Ataxia, Spinocerebellar, Type 14
X-Linked Cerebellar Ataxia
Spinocerebellar Ataxia 18	Spinocerebellar Ataxia Type 18 SCA18 Smna Sensorimotor Neuropathy With Ataxia, Autosomal Dominant Sensorimotor Neuropathy With Ataxia Autosomal Dominant
Schindler Disease	Alpha-N-Acetylgalactosaminidase Deficiency Naga Deficiency Alpha-Galactosidase B Deficiency Alpha-Galnac Deficiency, Schindler Type Alpha-Naga Deficiency Angiokeratoma Corporis Diffusum-Glycopeptiduria Galb Deficiency Kanzaki Disease Lysosomal Glycoaminoacid Storage Disease-Angiokeratoma Corporis Diffusum Neuroaxonal Dystrophy, Schindler Type Neuronal Axonal Dystrophy, Schindler Type Schindler Disease, Type I Schindler Disease, Type Ii
Spinocerebellar Ataxia, X-Linked 5	SCAX5 X-Linked Spinocerebellar Ataxia 5 X-Linked Non Progressive Cerebellar Ataxia
Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis	SANDO Mitochondrial Recessive Ataxia Syndrome Spinocerebellar Ataxia With Epilepsy Epilepsy, Progressive Myoclonic 5 Epm5 Miras SCAE Sensory Ataxic Neuropathy With Mitochondrial Dna Deletions, Autosomal Recessive Autosomal Recessive Sensory Ataxic Neuropathy With Mitochondrial Dna Deletions Progressive Myoclonic Epilepsy Type 5 Pme Type 5 Progressive Myoclonus Epilepsy Type 5 Sensory Ataxic Neuropathy-Dysarthria-Ophthalmoparesis Syndrome Recessive Mitochondrial Ataxia Syndrome Sensory Ataxic Neuropathy Dysarthria And Ophthalmoparesis Mitochondrial Spinocerebellar Ataxia-Epilepsy Syndrome Mscae Sensory Ataxic Neuropathy With Mitochondrial Dna Deletions Autosomal Recessive Progressive Myoclonic Epilepsy With Sensory Ataxic Neuropathy Epilepsy, Progressive Myoclonic, 5 Ataxia Neuropathy Spectrum
Autosomal Dominant Cerebellar Ataxia	Spinocerebellar Ataxia Adca Pierre Marie Cerebellar Ataxia Ataxia, Spinocerebellar Sca Autosomal Dominant Spinocerebellar Ataxia Spinocerebellar Ataxias
Cerebellar Disease	Cerebellar Diseases Cerebellar Dysfunction Cerebellar Abnormality Cerebellar Disorders

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14707	TMEM240 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TMEM240	MGD	MGI:3648074
Bos taurus	TMEM240	VGNC	VGNC:36051
Rattus norvegicus	TMEM240	RGD	RGD:2318117
Canis familiaris	TMEM240	VGNC	VGNC:47548
Felis catus	TMEM240	VGNC	VGNC:66324
Others	TMEM240	NCBI