INHBC - inhibin subunit beta C Gene

Also Known as IHBC

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3626

About INHBC

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:57,434,784-57,452,062 (from NCBI)

This gene has 1 transcript (splice variant), 197 orthologues and 31 paralogues. Restricted expression toward liver (RPKM 50.2).

Summary

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of Activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]

INHBC Products (1)

mRNA Protein Name
NM_005538.4 NP_005529.1 inhibin beta C chain preproprotein

INHBC Protein Structure

TGFb_propeptide

TGFb_propeptide: TGF-beta propeptide (33 - 208)

TGF_beta

TGF_beta: Transforming growth factor beta like domain (245 - 352)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

inhibin beta C chain

  • activin beta-C chain

Recombinant INHBC Proteins

Cat. No. Nom du produit Accession Pureté
HY-P70383 Inhibin beta C chain/INHBC Protein, Human (HEK293, His) P55103 (T19-S352) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS06815 INHBC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20964 Inhbc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27481 Inhbc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus INHBC VGNC VGNC:30202
Macaca mulatta INHBC VGNC VGNC:73745
Felis catus INHBC VGNC VGNC:84039
Mus musculus INHBC MGD MGI:105932
Canis familiaris INHBC VGNC VGNC:42023
Rattus norvegicus INHBC RGD RGD:621194
Others INHBC NCBI