MYO1D - myosin ID Gene

Also Known as myr4; PPP1R108

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4642

About MYO1D

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:32,492,522-32,877,124 (from NCBI)

This gene has 16 transcripts (splice variants), 204 orthologues and 43 paralogues. Broad expression in colon (RPKM 49.5), small intestine (RPKM 32.7) and 22 other tissues.

Summary

Enables protein domain specific binding activity. Predicted to be involved in actin filament organization; early endosome to recycling endosome transport; and vesicle transport along actin filament. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

MYO1D Products (4)

mRNA	Protein	Name
NM_001303279.2	NP_001290208.1	unconventional myosin-Id isoform 2
NM_001303280.2	NP_001290209.1	unconventional myosin-Id isoform 3
NM_001411088.1	NP_001398017.1	unconventional myosin-Id isoform 4
NM_015194.3	NP_056009.1	unconventional myosin-Id isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	22284616	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MYO1D Protein Structure

Myosin_head

IQ

Myosin_TH1

0
200
400
600
800
1006 a.a.

Protein Preferred Names	Protein Names
unconventional myosin-Id	myosin-I gamma

MYO1D Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P810106	Myosin Id Antibody (YA9450)	WB, ICC/IF, IF-Tissue, IP, ELISA	human, mouse, rat

Related Diseases

Diseases	Alias
Canavan Disease	Aspartoacylase Deficiency Aminoacylase 2 Deficiency Spongy Degeneration Of Central Nervous System Aspa Deficiency Acy2 Deficiency Canavan-Van Bogaert-Bertrand Disease Mild Canavan Disease Asp Deficiency Spongy Degeneration Of The Central Nervous System Severe Canavan Disease Von Bogaert-Bertrand Disease Canavan'S Disease Spongy Degeneration Of The Brain Juvenile Canavan Disease Infantile Canavan Disease Neonatal Canavan Disease CAND Disease, Canavan Canavan Disease, Juvenile Canavan Disease, Infantile Canavan Disease, Neonatal
Visceral Heterotaxy	Situs Ambiguus Heterotaxia Heterotaxy Syndrome Heterotaxy Lateralization Defect Situs Ambiguous Left Isomerism Htx Ivemark Syndrome Right Isomerism Situs Ambiguus Viscerum Incomplete Situs Inversus Partial Situs Inversus Heterotaxy, Visceral Asplenia Syndrome Bilateral Left-Sidedness Polysplenia Syndrome Moller Syndrome
Situs Inversus	Situs Inversus Viscerum Laterality Sequence Complete Transposition Siv

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08940	MYO1D Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MYO1D	VGNC	VGNC:68391
Canis familiaris	MYO1D	VGNC	VGNC:43563
Mus musculus	MYO1D	MGD	MGI:107728
Rattus norvegicus	MYO1D	RGD	RGD:621321
Macaca mulatta	MYO1D	VGNC	VGNC:75113
Bos taurus	MYO1D	VGNC	VGNC:31819
Others	MYO1D	NCBI