2. Gene
  3. PLCZ1 - Plcz1 phospholipase C, zeta 1 Gene

PLCZ1 - Plcz1 phospholipase C, zeta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 497197 | Gene type: protein coding

About PLCZ1

Summary

Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol Phospholipase C activity. Involved in positive regulation of cytosolic calcium ion concentration involved in egg activation. Located in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 17. Orthologous to human PLCZ1 (Phospholipase C zeta 1). [provided by Alliance of Genome Resources, Apr 2022]

PLCZ1 Products(1)

mRNA Protein Name
NM_001012234.2 NP_001012234.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cytosolic calcium ion concentration involved in egg activation IDA
IDA: Inferred from direct assay
18322275 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18322275 RGD
NOT located in pronucleus IDA
IDA: Inferred from direct assay
18322275 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

PLC-zeta-1

phosphoinositide phospholipase C-zeta-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10669 PLCZ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PLCZ1 NCBI NCBI:89869