SCAPER - S-phase cyclin A associated protein in the ER Gene

Homo sapiens

Also known as IDDRP; ZNF291; Zfp291; MSTP063

Gene ID: 49855 | Gene type: protein coding

About SCAPER

Cytogenetic location: 15q24.3 Genomic coordinates (GRCh38): 15:76,347,904-76,905,340 (from NCBI)

This gene has 23 transcripts (splice variants), 211 orthologues and is associated with 5 phenotypes. Broad expression in testis (RPKM 4.5), brain (RPKM 3.0) and 25 other tissues.

Summary

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

SCAPER Products(6)

mRNA	Protein	Name
NM_001145923.2	NP_001139395.1	S phase cyclin A-associated protein in the endoplasmic reticulum isoform b
NM_001353009.2	NP_001339938.1	S phase cyclin A-associated protein in the endoplasmic reticulum isoform c
NM_001353010.2	NP_001339939.1	S phase cyclin A-associated protein in the endoplasmic reticulum isoform d
NM_001353011.2	NP_001339940.1	S phase cyclin A-associated protein in the endoplasmic reticulum isoform e
NM_001353012.2	NP_001339941.1	S phase cyclin A-associated protein in the endoplasmic reticulum isoform d
NM_020843.4	NP_065894.2	S phase cyclin A-associated protein in the endoplasmic reticulum isoform a

SCAPER Protein Structure

zf-met

0
300
600
900
1200
1400 a.a.

Protein Preferred Names

Protein Names

S phase cyclin A-associated protein in the endoplasmic reticulum

zinc finger protein 291

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder And Retinitis Pigmentosa

IDDRP

Speech Disorder

Speech Disorders

Brachydactyly

Syndromic Rod-Cone Dystrophy

Syndromic Retinitis Pigmentosa

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder	ADHD
Attention Deficit Disorder	Attention Deficit-Hyperactivity Disorder, Susceptibility To
Attention Deficit Disorder With Hyperactivity	Hyperkinetic Disorder
Hyperactivity Of Childhood	Attention-Deficit/Hyperactivity Disorder
Add	Addh
Attention Deficit	Attention Deficit Disorder Of Childhood With Hyperactivity
Attention Deficit Disorder With Hyperactivity Syndrome	Hyperkinetic Syndrome
Attention-Deficit Hyperactivity Disorder	Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type
Disturbance Of Activity And Attention	Disorder Of Activity And Attention
Adhd - [Attention Deficit Hyperactivity Disorder]	Hyperkinetic Disorders
Disorder Of Activity And Attention With Hyperkinesia	Attention Deficit Syndrome With Hyperactivity

Late-Onset Retinal Degeneration

LORD	Retinal Degeneration, Late-Onset, Autosomal Dominant
Autosomal Dominant Late-Onset Retinal Degeneration	Pigmentary Retinopathy
Retinal Degeneration, Late-Onset	Retinitis Pigmentosa

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Body Mass Index Quantitative Trait Locus 11

OBESITY	Obesity, Susceptibility To
Leanness, Inherited	Obesity, Susceptibility To, Bmiq11
Obesity, Mild, Early-Onset	Obesity, Association With
Obesity, Early-Onset, Susceptibility To	Obesity, Severe
Obesity, Severe, And Type Ii Diabetes	Obesity, Late-Onset
Obesity , Susceptibility To	BMIQ11
Obesity Bmiq11	Obesity, Early-Onset
Simple Obesity Nos	Excess Fat
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified	Adiposis

Bardet-Biedl Syndrome

Bbs	Biedl-Bardet Syndrome

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Combined Oxidative Phosphorylation Deficiency 16

COXPD16	Infantile Hypertrophic Cardiomyopathy Due To Mrpl44 Deficiency
Combined Oxidative Phosphorylation Defect Type 16	Combined Oxidative Phosphorylation Deficiency, Type 16

Cardiomyopathy, Dilated, 1l

Dilated Cardiomyopathy 1l	CMD1L
Cardiomyopathy, Dilated 1l	Cardiomyopathy, Dilated, Type 1l

Blount'S Disease

Blount Disease	Tibia Vara
Osteochondrosis Deformans Tibiae	Osteochondrosis Deformans Tibiae, Familial Infantile Type
Familial Infantile Type Osteochondrosis Deformans Tibiae	Blount-Barber Syndrome
Erlacher-Blount Syndrome	Infantile Tibia Vara
Tibia Vara Blount	Blount Disease, Infantile

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12485	SCAPER Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SCAPER	VGNC	VGNC:34321
Felis catus	SCAPER	VGNC	VGNC:64899
Canis familiaris	SCAPER	VGNC	VGNC:45895
Rattus norvegicus	SCAPER	RGD	RGD:621585
Macaca mulatta	SCAPER	VGNC	VGNC:77006
Mus musculus	SCAPER	MGD	MGI:1925976

Name
Email *

	Sorry, but the email address you supplied was invalid.