Ndufs4 - NADH:ubiquinone oxidoreductase subunit S4 Gene

Rattus norvegicus

Also known as Aqdq

Gene ID: 499529 | Gene type: protein coding

About Ndufs4

Summary

Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in cellular respiration; positive regulation of fibroblast proliferation; and response to cAMP. Predicted to act upstream of or within several processes, including adult walking behavior; mitochondrial respiratory chain complex I assembly; and psychomotor behavior. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leigh disease and nuclear type mitochondrial complex I deficiency 1. Orthologous to human NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs4 Products(1)

mRNA	Protein	Name
NM_001025146.1	NP_001020317.1	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial precursor

Protein Preferred Names

Protein Names

NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

CI-18 kDa	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NADH-ubiquinone oxidoreductase 18 kDa subunit	complex I-18 kDa

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-172371	Hypoxystat		99.28%	Unkown
HY-121577	Sonlicromanol	Modulator	98.65%	Unkown
HY-RS09160	NDUFS4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-169281	Antiviral agent 61	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ndufs4	NCBI	NCBI:4724

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