ANGPTL3 - Angptl3 angiopoietin-like 3 Gene
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 502970
Summary
Predicted to enable growth factor activity; Integrin binding activity; and Phospholipase Inhibitor activity. Involved in response to hormone. Predicted to be located in Golgi apparatus; cell surface; and early endosome. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to human ANGPTL3 (angiopoietin like 3). [provided by Alliance of Genome Resources, Apr 2022]
ANGPTL3 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001025065.2 | NP_001020236.1 | angiopoietin-related protein 3 isoform 2 precursor |
| NM_001399252.1 | NP_001386181.1 | angiopoietin-related protein 3 isoform 1 precursor |
| NM_001399253.1 | NP_001386182.1 | angiopoietin-related protein 3 isoform 3 precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
angiopoietin-related protein 3 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-153497A | Vupanorsen sodium | Inhibitor | 98.33% | Phase 2 |
| HY-153497 | Vupanorsen | Inhibitor | 92.29% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-185318A | Lexosiran sodium | Inhibitor | / | Unkown |
| HY-185318 | Lexosiran | Inhibitor | / | Unkown |
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