NLRP1 - NLR family pyrin domain containing 1 Gene
Species: Bos taurus
Gene Type: protein coding
Gene ID: 528166
About NLRP1
Primary_assembly 19: 26,027,728-26,059,636 forward strand.ARS-UCD1.2:CM008186.2
This gene has 4 transcripts (splice variants), 93 orthologues and 16 paralogues.
NLRP1 Products (11)
| mRNA | Protein | Name |
|---|---|---|
| XM_024980721.1 | XP_024836489.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X6 |
| XM_024980726.1 | XP_024836494.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X9 |
| XM_010815959.2 | XP_010814261.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X5 |
| XM_003587406.4 | XP_003587454.2 | NACHT, LRR and PYD domains-containing protein 1 isoform X1 |
| XM_010815958.2 | XP_010814260.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X3 |
| XM_024980720.1 | XP_024836488.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X4 |
| XM_024980719.1 | XP_024836487.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X2 |
| XM_024980725.1 | XP_024836493.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X8 |
| XM_024980722.1 | XP_024836490.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X7 |
| XM_024980724.1 | XP_024836492.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X8 |
| XM_024980723.1 | XP_024836491.1 | NACHT, LRR and PYD domains-containing protein 1 isoform X8 |
NLRP1 Protein Structure
NACHT
NACHT: pfam05729 (293 - 462)
NOD2_WH
NOD2_WH: pfam17779 (532 - 586)
NLRC4_HD2
NLRC4_HD2: pfam17776 (588 - 700)
LRR_RI
LRR_RI: sd00033 (777 - 805)
PPP1R42
PPP1R42: cl42388 (777 - 950)
LRR_RI
LRR_RI: sd00033 (806 - 833)
LRR_RI
LRR_RI: sd00033 (834 - 858)
LRR_RI
LRR_RI: sd00033 (863 - 890)
LRR_RI
LRR_RI: sd00033 (891 - 919)
FIIND
FIIND: pfam13553 (1039 - 1291)
CARD_ASC_NALP1
CARD_ASC_NALP1: cd08330 (1317 - 1397)
- 0
- 300
- 600
- 900
- 1200
- 1410 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
NACHT, LRR and PYD domains-containing protein 1 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-127090 | Muramyl dipeptide | Agonist | 99.07% | Phase 3 |
Pre-clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-156798 | ADS032 | Inhibitor | 99.89% | Unkown |
| HY-178898 | 7-Oxogedunin | Inhibitor | / | Unkown |
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