CSNK1G1 - casein kinase 1 gamma 1 Gene

Homo sapiens

Also known as CK1gamma1

Gene ID: 53944 | Gene type: protein coding

About CSNK1G1

Cytogenetic location: 15q22.31 Genomic coordinates (GRCh38): 15:64,165,525-64,356,173 (from NCBI)

This gene has 18 transcripts (splice variants), 302 orthologues, 12 paralogues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 6.6), thyroid (RPKM 4.2) and 25 other tissues.

Summary

This gene encodes a member of the Casein Kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]

CSNK1G1 Products(4)

mRNA	Protein	Name
NM_001329605.2	NP_001316534.1	casein kinase I isoform gamma-1 isoform 2
NM_001329606.2	NP_001316535.1	casein kinase I isoform gamma-1 isoform 1
NM_001329607.2	NP_001316536.1	casein kinase I isoform gamma-1 isoform 3
NM_022048.5	NP_071331.2	casein kinase I isoform gamma-1 isoform 1

CSNK1G1 Protein Structure

Pkinase

CK1gamma_C

0
100
200
300
422 a.a.

Protein Preferred Names

Protein Names

casein kinase I isoform gamma-1

Recombinant CSNK1G1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76850	CSNK1G1 Protein, Human (sf9, His-GST)	Q9HCP0-1 (M1-K422)	≥95%

Related Diseases

Diseases

Alias

Aortic Valve Prolapse

Gm1-Gangliosidosis, Type I

Gm1 Gangliosidosis Type 1	Beta-Galactosidase-1 Deficiency
Infantile Gm1 Gangliosidosis	GM1G1
Gangliosidosis, Generalized Gm1, Type 1	Glb1 Deficiency
Gangliosidosis Generalized Gm1 Type 1	Gangliosidosis, Generalized Gm1, Type I
Gangliosidosis, Generalized Gm1, Infantile Form	Beta Galactosidase Deficiency Type 1
Glb Deficiency Type 1	Gangliosidosis Generalized Gm1 Infantile Form
Norman-Landing Disease	Gm1-Gangliosidosis 1
Gangliosidosis Generalized Gm1 Infantile Type	Gm1-Gangliosidosis Infantile
Gangliosidosis Gm1 Infantile	Gangliosidosis, Gm1, Type I
Gangliosidosis Gm1	Beta-Galactosidase Deficiency

Epilepsy

Epilepsy Syndrome	Epileptic Syndrome
Epilepsies	Symptomatic Epilepsies
Post Traumatic Epilepsy	Traumatic Epilepsy
Traumatic Epileptic	Epilepsy Due To Hippocampal Sclerosis
Epilepsy With Ammon'S Horn Sclerosis	Epilepsy Due To Cortical Dysplasia
Epilepsy Due To Neuronal Migration Disorders

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03248	CSNK1G1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CSNK1G1	RGD	RGD:621404
Felis catus	CSNK1G1	VGNC	VGNC:80998
Bos taurus	CSNK1G1	VGNC	VGNC:50095
Macaca mulatta	CSNK1G1	VGNC	VGNC:81383
Mus musculus	CSNK1G1	MGD	MGI:2660884
Canis familiaris	CSNK1G1	VGNC	VGNC:54937
Others	CSNK1G1	NCBI

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