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  3. CSNK1G3 - casein kinase 1 gamma 3 Gene

CSNK1G3 - casein kinase 1 gamma 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CSNK1G3L; CKI-gamma 3

Gene ID: 1456 | Gene type: protein coding

About CSNK1G3

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:123,512,177-123,617,049 (from NCBI)

This gene has 11 transcripts (splice variants), 127 orthologues and 12 paralogues. Ubiquitous expression in colon (RPKM 8.2), small intestine (RPKM 7.3) and 25 other tissues.

Summary

This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

CSNK1G3 Products(16)

mRNA Protein Name
NM_001031812.4 NP_001026982.1 casein kinase I isoform gamma-3 isoform 2
NM_001044723.2 NP_001038188.1 casein kinase I isoform gamma-3 isoform 4
NM_001270572.1 NP_001257501.1 casein kinase I isoform gamma-3 isoform 5
NM_001270573.2 NP_001257502.1 casein kinase I isoform gamma-3 isoform 6
NM_001270574.2 NP_001257503.1 casein kinase I isoform gamma-3 isoform 7
NM_001364140.2 NP_001351069.1 casein kinase I isoform gamma-3 isoform 8
NM_001364141.2 NP_001351070.1 casein kinase I isoform gamma-3 isoform 9
NM_001364143.2 NP_001351072.1 casein kinase I isoform gamma-3 isoform 10
NM_001364144.2 NP_001351073.1 casein kinase I isoform gamma-3 isoform 11
NM_001364145.2 NP_001351074.1 casein kinase I isoform gamma-3 isoform 12
NM_001364146.2 NP_001351075.1 casein kinase I isoform gamma-3 isoform 13
NM_001364147.2 NP_001351076.1 casein kinase I isoform gamma-3 isoform 14
NM_001364148.2 NP_001351077.1 casein kinase I isoform gamma-3 isoform 15
NM_001364149.2 NP_001351078.1 casein kinase I isoform gamma-3 isoform 6
NM_001364150.2 NP_001351079.1 casein kinase I isoform gamma-3 isoform 6
NM_004384.5 NP_004375.2 casein kinase I isoform gamma-3 isoform 1

CSNK1G3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (43 - 297)

CK1gamma_C

CK1gamma_C: Casein kinase 1 gamma C terminal (328 - 417)

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  • 447 a.a.
Protein Preferred Names Protein Names

casein kinase I isoform gamma-3

casein kinase I

Related Diseases

Diseases Alias
Sarcosinemia

Sarcosine Dehydrogenase Complex Deficiency

Sard Deficiency

Sardh Deficiency

SARCOS

Hypersarcosinemia

Sardhd

Demethylation Defect Of N-Methylglycine
Lissencephaly 8

LIS8
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03250 CSNK1G3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CSNK1G3 MGD MGI:1917675
Felis catus CSNK1G3 VGNC VGNC:97392
Canis familiaris CSNK1G3 VGNC VGNC:39669
Bos taurus CSNK1G3 VGNC VGNC:27768
Rattus norvegicus CSNK1G3 RGD RGD:621408
Macaca mulatta CSNK1G3 VGNC VGNC:81384
Others CSNK1G3 NCBI