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55007

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By Targets:	Apoptosis (2) Autophagy (1) Biochemical Assay Reagents (1) Complement System (1) Fluorescent Dye (1) HIV (1) MicroRNA (8) PAI-1 (1)
By Research Areas:	Cancer (9) Infection (1) Inflammation/Immunology (2)
Oligonucleotides:	miRNA mimics (2) miRNA antagomirs (2) miRNA agomirs (2) MicroRNAs (8) miRNA inhibitors (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116282A

*Dextran sulfate sodium salt (MW 4500-5500)* DSS (MW 4500-5500); DXS (MW 4500-5500)	HIV Apoptosis Complement System	Infection Inflammation/Immunology
Dextran sulfate sodium salt (DSS) (MW 4500-5500) is a polymer of dehydrated glucose with a molecular weight of approximately 4500-5500. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 4500-5500) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 4500-5500) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (MW 4500-5500) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) inhibits instant blood-mediated inflammatory reaction (IBMIR) .

HY-112624K

Dextran T5 (MW 5,000) Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)	Apoptosis Autophagy	Others
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-B1620M

Polyvinylpyrrolidone, average Mw～55000 PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~55000 is a multifunctional synthetic polymer with an average molecular weight of 55000 Da. Polyvinylpyrrolidone, average Mw~55000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~55000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-119160

TM5007	PAI-1	Inflammation/Immunology Cancer
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC₅₀ of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung .

HY-D2848A

*Chitosan-Cy5.5 (MW 55000)*	Fluorescent Dye	Others
Chitosan-Cy5.5 (MW 55000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 55000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .

HY-R01498

*hsa-miR-5007-5p mimic*	MicroRNA	Cancer
hsa-miR-5007-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5007-5p mimic hsa-miR-5007-5p mimic

HY-R01497

*hsa-miR-5007-3p mimic*	MicroRNA	Cancer
hsa-miR-5007-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5007-3p mimic hsa-miR-5007-3p mimic

HY-R01498A

*hsa-miR-5007-5p agomir*	MicroRNA	Cancer
hsa-miR-5007-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5007-5p agomir hsa-miR-5007-5p agomir

HY-RI01497

*hsa-miR-5007-3p inhibitor*	MicroRNA	Cancer
hsa-miR-5007-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5007-3p inhibitor hsa-miR-5007-3p inhibitor

HY-RI01497A

*hsa-miR-5007-3p antagomir*	MicroRNA	Cancer
hsa-miR-5007-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5007-3p antagomir hsa-miR-5007-3p antagomir

HY-R01497A

*hsa-miR-5007-3p agomir*	MicroRNA	Cancer
hsa-miR-5007-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5007-3p agomir hsa-miR-5007-3p agomir

HY-RI01498A

*hsa-miR-5007-5p antagomir*	MicroRNA	Cancer
hsa-miR-5007-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5007-5p antagomir hsa-miR-5007-5p antagomir

HY-RI01498

*hsa-miR-5007-5p inhibitor*	MicroRNA	Cancer
hsa-miR-5007-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5007-5p inhibitor hsa-miR-5007-5p inhibitor

*Chitosan-Cy5.5 (MW 55000)*	Fluorescent Dyes
Chitosan-Cy5.5 (MW 55000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 55000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .

Cat. No.	Product Name	Type

HY-112624K

Dextran T5 (MW 5,000) Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)	Biochemical Assay Reagents
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

Dextran T5 (MW 5,000)

Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)

Biochemical Assay Reagents

Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-B1620M

Polyvinylpyrrolidone, average Mw～55000 PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000	Biochemical Assay Reagents
Polyvinylpyrrolidone, average Mw~55000 is a multifunctional synthetic polymer with an average molecular weight of 55000 Da. Polyvinylpyrrolidone, average Mw~55000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~55000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

Polyvinylpyrrolidone, average Mw～55000

PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000

Biochemical Assay Reagents

Polyvinylpyrrolidone, average Mw~55000 is a multifunctional synthetic polymer with an average molecular weight of 55000 Da. Polyvinylpyrrolidone, average Mw~55000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~55000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

Host:	Mouse (3)
Reactivity:	Human (3) Rat (1) Mouse (2)
Application:	ICC/IF (3) IF-Tissue (1) IP (1) WB (3) ELISA (3)
Isotype:	IgG3 (1) IgG2b,IgG/Kappa (1)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (3)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85815

	CD27 Antibody (YA5507)	WB, ICC/IF, ELISA	Human
	CD27 Antibody (YA5507) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD27.

HY-P85315

	PARL Antibody (YA5007) PARL; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL	WB, ICC/IF, IP, ELISA, IF-Tissue	Human, Mouse, Rat
	PARL Antibody (YA5007) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PARL.

HY-P85808

	Bcl-6 Antibody (YA5500) BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51	WB, ICC/IF, ELISA	Human, Mouse
	Bcl-6 Antibody (YA5500) is a Mouse-derived and non-conjugated IgG3 monoclonal antibody, targeting to Bcl-6.

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Cat. No.	Product Name		Classification

HY-R01498

*hsa-miR-5007-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-5007-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01497

*hsa-miR-5007-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-5007-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01498A

*hsa-miR-5007-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5007-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01497

*hsa-miR-5007-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5007-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01497A

*hsa-miR-5007-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5007-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01497A

*hsa-miR-5007-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5007-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01498A

*hsa-miR-5007-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5007-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01498

*hsa-miR-5007-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5007-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

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