RCN3 - reticulocalbin 3 Gene

Homo sapiens

Also known as RLP49

Gene ID: 57333 | Gene type: protein coding

About RCN3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,528,003-49,543,633 (from NCBI)

This gene has 5 transcripts (splice variants), 105 orthologues and 4 paralogues. Ubiquitous expression in fat (RPKM 12.8), placenta (RPKM 11.9) and 24 other tissues.

Summary

Enables calcium ion binding activity. Involved in several processes, including collagen biosynthetic process; positive regulation of peptidase activity; and regulation of protein kinase B signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

RCN3 Products(1)

mRNA	Protein	Name
NM_020650.3	NP_065701.2	reticulocalbin-3 precursor

RCN3 Protein Structure

EF-hand_7

EF-hand_5

EF-hand_8

0
100
200
300
328 a.a.

Protein Preferred Names

Protein Names

reticulocalbin-3

EF-hand calcium-binding protein RLP49

Recombinant RCN3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71253	RCN3 Protein, Human (HEK293, His)	Q96D15 (K21-L328)	≥95%

Related Diseases

Diseases

Alias

Myopathy, Distal, 3

MPD3	Distal Muscular Dystrophy 3
Distal Myopathy Type 3	Myopathy, Distal 3
Distal Myopathy 3	Finnish Upper Limb-Onset Distal Myopathy

Neonatal Respiratory Failure

Respiratory Failure Of Newborn	Inadequate Pulmonary Ventilation Of Newborn
Newborn Lung Insufficiency	Newborn Pulmonary Function Inadequate
Newborn Pulmonary Insufficiency	Newborn Respiration Failure
Newborn Respiratory Insufficiency	Respiratory Insufficiency Syndrome Of Newborn

Enchondromatosis, Multiple, Ollier Type

Ollier Disease	Enchondromatosis
Dyschondroplasia	Osteochondromatosis
Multiple Cartilaginous Enchondroses	Multiple Enchondromatosis
Enchondromatosis With Haemangiomata	Enchondromatosis, Multiple
Kast'S Syndrome	Ollier'S Syndrome
Enchondromatosis Multiple	ENCHOM
Maffucci Disease	Olliers Disease
Hereditary Multiple Exostoses	Chondromatosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11790	RCN3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RCN3	VGNC	VGNC:33833
Canis familiaris	RCN3	VGNC	VGNC:45445
Mus musculus	RCN3	MGD	MGI:1277122
Rattus norvegicus	RCN3	RGD	RGD:1359365
Others	RCN3	NCBI