THADA - THADA armadillo repeat containing Gene

Homo sapiens

Also known as GITA; ARMC13; Trm732

Gene ID: 63892 | Gene type: protein coding

About THADA

Cytogenetic location: 2p21 Genomic coordinates (GRCh38): 2:43,230,851-43,596,038 (from NCBI)

This gene has 19 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in lymph node (RPKM 6.5), thyroid (RPKM 6.2) and 25 other tissues.

Summary

This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and Apoptosis. [provided by RefSeq, Sep 2016]

THADA Products(7)

mRNA	Protein	Name
NM_001083953.2	NP_001077422.1	thyroid adenoma-associated protein isoform a
NM_001271643.2	NP_001258572.1	thyroid adenoma-associated protein isoform b
NM_001271644.2	NP_001258573.1	thyroid adenoma-associated protein isoform c
NM_001345923.2	NP_001332852.1	thyroid adenoma-associated protein isoform d
NM_001345924.2	NP_001332853.1	thyroid adenoma-associated protein isoform e
NM_001345925.2	NP_001332854.1	thyroid adenoma-associated protein isoform a
NM_022065.5	NP_071348.3	thyroid adenoma-associated protein isoform a

THADA Protein Structure

DUF2428

0
300
600
900
1200
1500
1800
1953 a.a.

Protein Preferred Names

Protein Names

thyroid adenoma-associated protein

Trm732 homolog

Related Diseases

Diseases

Alias

Adenoma

Acinar Cell Adenoma	Adenomas
Acinic Cell Adenoma

Polycystic Ovary Syndrome

Polycystic Ovarian Syndrome	Pcos
Polycystic Ovarian Disease	Polycystic Ovaries
Stein-Leventhal Syndrome	Multicystic Ovaries
Polycystic Ovary	Sclerocystic Ovaries
Sclerocystic Ovary Syndrome	Stein-Leventhal Synd.
Cystic Disease Of Ovaries	Cystic Disease Of Ovary
Pco	Pcod
Sclerocystic Ovarian Degeneration	Polycystic Ovary Syndrome, Susceptibility To
Pcos - [Polycystic Ovary Syndrome]	Polycystic Ovary Nos
Pco - [Polycystic Ovary]

Hyperinsulinemic Hypoglycemia, Familial, 5

Hyperinsulinism Due To Insr Deficiency	HHF5
Familial Hyperinsulinemic Hypoglycemia 5	Hyperinsulinemic Hypoglycemia Due To Insr Deficiency
Hyperinsulinemic Hypoglycemia Due To Insulin Receptor Deficiency	Congenital Hyperinsulinism
Persistent Hyperinsulinemic Hypoglycemia Of Infancy	Phhi
Hyperinsulinemic Hypoglycemia Familial 5

Wolfram Syndrome 1

WFS1	Didmoad
Wfs	Diabetes Mellitus And Insipidus With Optic Atrophy And Deafness
Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness	Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Syndrome
Wolfram Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14468	THADA Human Pre-designed siRNA Set A		/	Unkown

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