2. Gene
  3. DMRTA1 - DMRT like family A1 Gene

DMRTA1 - DMRT like family A1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DMO; DMRT4

Gene ID: 63951 | Gene type: protein coding

About DMRTA1

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:22,446,824-22,455,740 (from NCBI)

This gene has 1 transcript (splice variant), 178 orthologues and 8 paralogues. Broad expression in liver (RPKM 4.0), kidney (RPKM 3.0) and 19 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in germ cell development; regulation of transcription by RNA polymerase II; and sex differentiation. Predicted to act upstream of or within male mating behavior and ovarian follicle development. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DMRTA1 Products(1)

mRNA Protein Name
NM_022160.3 NP_071443.2 doublesex- and mab-3-related transcription factor A1

DMRTA1 Protein Structure

DM

DM: DM DNA binding domain (93 - 139)

DMA

DMA: DMRTA motif (327 - 364)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 504 a.a.
Protein Preferred Names Protein Names

doublesex- and mab-3-related transcription factor A1

Related Diseases

Diseases Alias
Dermoid Cyst Of Ovary

Dermoid Cyst

Ovarian Dermoid Cyst

Teratoma, Ovarian
Diabetes Mellitus, Neonatal, With Congenital Hypothyroidism

Neonatal Diabetes Mellitus With Congenital Hypothyroidism

Ndh Syndrome

NDH

Neonatal Diabetes-Congenital Hypothyroidism-Congenital Glaucoma-Hepatic Fibrosis-Polycystic Kidneys Syndrome
Dermatopathia Pigmentosa Reticularis

DPR
Chronic Wasting Disease

Wasting Disease, Chronic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03831 DMRTA1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DMRTA1 VGNC VGNC:51707
Bos taurus DMRTA1 VGNC VGNC:28113
Rattus norvegicus DMRTA1 RGD RGD:1309796
Macaca mulatta DMRTA1 VGNC VGNC:108198
Felis catus DMRTA1 VGNC VGNC:61530
Mus musculus DMRTA1 MGD MGI:2653627