Hyal2 - hyaluronidase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64468

Summary

Enables hyaluronoglucuronidase activity. Involved in several processes, including hyaluronan catabolic process; positive regulation of urine volume; and renal water absorption. Located in Golgi membrane and membrane raft. Is anchored component of plasma membrane. Biomarker of pulmonary hypertension. Orthologous to human HYAL2 (hyaluronidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hyal2 Products (1)

mRNA Protein Name
NM_172040.2 NP_742037.2 hyaluronidase-2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables hyaluronoglucuronidase activity IDA
IDA: Inferred from direct assay
19635555 RGD
Biological Process GO Annotation Evidence References Source
involved in hyaluronan catabolic process IDA
IDA: Inferred from direct assay
19635555 RGD
involved in kidney development IEP
IEP: Inferred from expression pattern
17706761 RGD
involved in positive regulation of urine volume IEP
IEP: Inferred from expression pattern
19635555 RGD
involved in renal water absorption IEP
IEP: Inferred from expression pattern
19635555 RGD
involved in symbiont entry into host cell IDA
IDA: Inferred from direct assay
12584308 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
21740893 RGD
located in membrane raft IDA
IDA: Inferred from direct assay
21740893 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
21740893 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hyaluronidase-2

  • hyal-2

  • hyaluronoglucosaminidase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2096 Hexapeptide-11 99.77% Unkown
HY-E70182 Hyaluronidase 2 Inhibitor / Unkown
HY-RS06496 HYAL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hyal2 NCBI NCBI:8692
Mus musculus Hyal2 NCBI NCBI:15587