Nmi - N-myc (and STAT) interactor Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64685

Summary

Predicted to enable identical protein binding activity. Involved in positive regulation of defense response; response to virus; and Toll-like Receptor 4 signaling pathway. Acts upstream of or within negative regulation of innate immune response; negative regulation of type I interferon production; and positive regulation of protein K48-linked ubiquitination. Located in extracellular space. Is expressed in genitourinary system; limb; and retina. Orthologous to human NMI (N-myc and STAT interactor). [provided by Alliance of Genome Resources, Apr 2022]

Nmi Products (3)

mRNA Protein Name
NM_001141948.1 NP_001135420.1 N-myc-interactor
NM_001141949.1 NP_001135421.1 N-myc-interactor
NM_019401.2 NP_062274.1 N-myc-interactor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23956435 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of innate immune response IDA
IDA: Inferred from direct assay
23956435 MGI
acts upstream of or within negative regulation of interferon-alpha production IMP
IMP: Inferred from mutant phenotype
23956435 MGI
acts upstream of or within negative regulation of interferon-beta production IMP
IMP: Inferred from mutant phenotype
23956435 MGI
acts upstream of or within negative regulation of type I interferon production IGI
IGI: Inferred from genetic interaction
23956435 MGI
involved in positive regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
29038465 MGI
involved in positive regulation of innate immune response IMP
IMP: Inferred from mutant phenotype
29038465 MGI
acts upstream of or within positive regulation of protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
23956435 MGI
acts upstream of protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
23956435 MGI
involved in response to virus IMP
IMP: Inferred from mutant phenotype
23956435 MGI
involved in toll-like receptor 4 signaling pathway IDA
IDA: Inferred from direct assay
29038465 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
29038465 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-myc-interactor

  • N-mcy (and STAT) interactor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101540 NMI 8739 Agonist 99.91% Unkown
HY-180370 Nitromemantine Antagonist / Unkown
HY-RS08939 MYO1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09381 NMI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21659 Myo1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nmi NCBI NCBI:9111