Adgrl1 - adhesion G protein-coupled receptor L1 Gene

Also Known as CL1BA; Lphn1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65096

Summary

Enables cell adhesion molecule binding activity; toxic substance binding activity; and transmembrane signaling receptor activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and positive regulation of synapse maturation. Located in growth cone; postsynaptic density; and presynaptic membrane. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Orthologous to human ADGRL1 (adhesion G protein-coupled receptor L1). [provided by Alliance of Genome Resources, Apr 2022]

Adgrl1 Products (1)

mRNA Protein Name
NM_022962.1 NP_075251.1 adhesion G protein-coupled receptor L1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
9261169 RGD
enables cell adhesion molecule binding IDA
IDA: Inferred from direct assay
21724987 RGD
enables latrotoxin receptor activity IDA
IDA: Inferred from direct assay
9261169 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10964907 RGD
enables toxic substance binding IPI
IPI: Inferred from physical interaction
9261169 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
21724987 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21724987 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21724987 RGD
located in growth cone IDA
IDA: Inferred from direct assay
21724987 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
21724987 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
21724987 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
21724987 RGD
located in presynaptic membrane IDA
IDA: Inferred from direct assay
21724987 RGD
is active in presynaptic membrane IMP
IMP: Inferred from mutant phenotype
21724987 RGD
located in synapse IDA
IDA: Inferred from direct assay
21724987 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor L1

  • CIRL-1

  • calcium-independent alpha-latrotoxin receptor 1

  • latrophilin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00361 ADGRL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184118 ADGRL1-IN-1 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrl1 NCBI NCBI:22859