ADGRL1-IN-1
ADGRL1-IN-1 is a ADGRL1 inhibitor. ADGRL1-IN-1 activates the GSK3β-STAT1 signaling axis. ADGRL1-IN-1 induces anti-tumor immunity in a CT26 colorectal cancer mouse model. ADGRL1-IN-1 can be used in studies related to colorectal cancer.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 693829-95-7
- 分子式: C16H9BrF3NO
- 分子量:368.15
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
GSK-3β |
STAT1 |
体外実験
ADGRL1-IN-1 (Compound 2) (15 mM) binds directly to ADGRL1 in CT26 cells, as evidenced by its ability to protect the receptor from protease degradation at a concentration of 15 mM[1].
ADGRL1-IN-1 activates the GSK3β-STAT1 axis in CT26 cells and induces BMDC activation via factors secreted by CT26 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 693829-95-7
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分子量 368.15
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分子式 C16H9BrF3NO
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SMILES
FC(C1=CN=C(OC2=CC=C3C=CC=CC3=C2Br)C=C1)(F)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)