OCM - oncomodulin Gene

Also Known as OM; OCM1; ONCM

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 654231

About OCM

Cytogenetic location: 7p22.1 Genomic coordinates (GRCh38): 7:5,859,718-5,886,363 (from NCBI)

This gene has 2 transcripts (splice variants), 148 orthologues and 2 paralogues. Low expression observed in reference dataset.

Summary

Oncomodulin is a high-affinity calcium ion-binding protein. It belongs to the superfamily of Calmodulin proteins, also known as the EF-hand proteins. Oncomodulin is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors. [provided by RefSeq, Jul 2008]

OCM Products (3)

mRNA	Protein	Name
NM_001097622.2	NP_001091091.1	oncomodulin-1 isoform a
NM_001391990.1	NP_001378919.1	oncomodulin-1 isoform a
NM_001391991.1	NP_001378920.1	oncomodulin-1 isoform b

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OCM Protein Structure

EF-hand_7

0
100
109 a.a.

Protein Preferred Names	Protein Names
oncomodulin-1	beta parvalbumin

OCM Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	OCM	P0CE72	CKMT1A	Homo sapiens	P12532	Y2H Array	32296183
Intra	OCM	P0CE72	CKMT1A	Homo sapiens	P12532	MAPPIT	32296183
Intra	OCM	P0CE72	CKMT1A	Homo sapiens	P12532	Y2H Prey Pooling	32296183
Intra	OCM	P0CE72	CKMT1A	Homo sapiens	P12532	Validated Y2H	32296183
Intra	OCM	P0CE72	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	32296183
Intra	OCM	P0CE72	SDCBP	Homo sapiens	O00560	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant OCM Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71100	Oncomodulin-1 Protein, Human (His)	P0CE72 (M1-S109)	≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases	Alias
Fish Allergy	Allergy To Fish
Vulvar Leiomyoma
Vulvar Benign Neoplasm
Vegetable Allergy
Capillary Malformations, Congenital	Familial Multiple Nevi Flammei Nevi Flammei, Familial Multiple CMC Port-Wine Stain Capillary Malformations Cmal Familial Multiple Port-Wine Stains Capillary Malformation Capillary Malformations, Congenital, 1, Somatic, Mosaic Congenital Capillary Malformations Port-Wine Stain Familial Multiple Hereditary Capillary Malformations Capillary Malformations, Hereditary Capillary Malformations, Congenital, Type 1, Somatic, Mosaic Strawberry Nevus Of Skin Naevus Flammeus
Bartholin'S Duct Cyst	Bartholin Duct Cyst Bartholin'S Cyst Cyst Of Bartholin'S Gland Duct Cyst Of Bartholin'S Gland Vulvovaginal Cyst Cyst Of Bartholin Gland Duct
Deafness, Autosomal Dominant 27	DFNA27 Autosomal Dominant Nonsyndromic Deafness 27 Autosomal Dominant Deafness 27 Deafness, Autosomal Dominant, 27
Enterobiasis	Oxyuriasis Pinworm Infection Enterobius Vermicularis Infection Threadworm Infection Oxyuris Vermicularis Infection Enterobiosis Pinworm Pinworm Disease Seatworm Infection Enterobiasis Threadworm Pinworm Infestation Seatworm
Vulvar Leiomyosarcoma
Deafness, Autosomal Dominant 50	DFNA50 Autosomal Dominant Nonsyndromic Deafness 50 Autosomal Dominant Deafness 50 Deafness, Autosomal Dominant, Type 50
Acute Hemorrhagic Leukoencephalitis	Ahl Acute Haemorrhagic Leucoencephalitis Of Weston Hurst Leukoencephalitis, Acute Hemorrhagic Acute Hemorrhagic Encephalomyelitis Acute Necrotizing Hemorrhagic Leukoencephalitis Weston-Hurst Syndrome Ahle Acute Haemorrhagic Leucoencephalitis Hurst Disease Acute Haemorrhagic Leukoencephalitis, Postimmunization Or Postvaccinal Postimmunization Or Postvaccinal Leukoencephalopathy
Vertigo, Benign Recurrent	Benign Paroxysmal Positional Vertigo Bppv Vestibulopathy, Familial BRV Vertigo, Benign Paroxysmal Positional Benign Paroxysmal Positional Nystagmus Benign Recurrent Vertigo Familial Benign Recurrent Vertigo Familial Vestibulopathy Benign Paroxysmal Nystagmus Bppv - [Benign Positional Paroxysmal Vertigo]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09744	OCM Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS09745	OCM2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	OCM	MGD	MGI:97401
Rattus norvegicus	OCM	RGD	RGD:3222
Others	OCM	NCBI