Twsg1 - twisted gastrulation BMP signaling modulator 1 Gene

Also Known as Tsg; Twg; D17Ertd403e; 1810013J15Rik; 9030422N06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65960

Summary

Predicted to enable transforming growth factor beta binding activity. Acts upstream of or within several processes, including animal organ development; negative regulation of osteoblast differentiation; and regulation of BMP signaling pathway. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; sensory organ; and skeleton. Orthologous to human TWSG1 (twisted gastrulation BMP signaling modulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Twsg1 Products (1)

mRNA Protein Name
NM_023053.4 NP_075540.1 twisted gastrulation protein homolog 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparin binding IDA
IDA: Inferred from direct assay
15381701 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15381701 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within BMP signaling pathway IGI
IGI: Inferred from genetic interaction
14681194 MGI
acts upstream of or within camera-type eye development IGI
IGI: Inferred from genetic interaction
14681194 MGI
acts upstream of or within chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
14681194 MGI
acts upstream of or within embryo development IMP
IMP: Inferred from mutant phenotype
15013800 MGI
acts upstream of or within forebrain development IGI
IGI: Inferred from genetic interaction
14681194 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
15013800 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
12665593 MGI
acts upstream of or within mesoderm formation IGI
IGI: Inferred from genetic interaction
15843411 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
15780974 MGI
acts upstream of or within negative regulation of BMP signaling pathway IMP
IMP: Inferred from mutant phenotype
12665593 MGI
acts upstream of or within negative regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
15780974 MGI
acts upstream of or within ossification IMP
IMP: Inferred from mutant phenotype
12665593 MGI
acts upstream of or within positive regulation of BMP signaling pathway IMP
IMP: Inferred from mutant phenotype
12665593 MGI
acts upstream of or within salivary gland morphogenesis IMP
IMP: Inferred from mutant phenotype
16289463 MGI
acts upstream of or within tissue development IGI
IGI: Inferred from genetic interaction
14681194 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15780974 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

twisted gastrulation protein homolog 1

  • twisted gastrulation homolog 1

Recombinant Twsg1 Proteins

Cat. No. Product Name Accession Purity
HY-P77267 TWSG1 Protein, Mouse (HEK293, His) Q9EP52 (C25-F222) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15284 TWSG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17999 Twsg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24471 Twsg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Twsg1 NCBI NCBI:57045