Actr2 - ARP2 actin-related protein 2 Gene

Also Known as Arp2; D6Ertd746e; 4921510D23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66713

Summary

Predicted to enable cytoskeletal protein binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cellular response to interferon-gamma; meiotic chromosome movement towards spindle pole; and meiotic cytokinesis. Located in actin cap. Is expressed in metanephros. Orthologous to human ACTR2 (actin related protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Actr2 Products (2)

mRNA Protein Name
NM_001362899.1 NP_001349828.1 actin-related protein 2 isoform 1
NM_146243.2 NP_666355.1 actin-related protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31146259 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21874009 MGI
acts upstream of or within asymmetric cell division IGI
IGI: Inferred from genetic interaction
21494665 MGI
acts upstream of or within cellular response to type II interferon IGI
IGI: Inferred from genetic interaction
19144319 MGI
acts upstream of or within cytosolic transport IMP
IMP: Inferred from mutant phenotype
21874009 MGI
acts upstream of or within establishment or maintenance of cell polarity IGI
IGI: Inferred from genetic interaction
21494665 MGI
acts upstream of or within meiotic cell cycle IGI
IGI: Inferred from genetic interaction
21494665 MGI
acts upstream of or within meiotic chromosome movement towards spindle pole IGI
IGI: Inferred from genetic interaction
23439682 MGI
acts upstream of or within meiotic cytokinesis IGI
IGI: Inferred from genetic interaction
21494665 MGI
acts upstream of or within spindle localization IGI
IGI: Inferred from genetic interaction
21494665 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cap IDA
IDA: Inferred from direct assay
21494665 MGI
located in cell cortex IDA
IDA: Inferred from direct assay
21494665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

actin-related protein 2

  • ARP2 actin-related protein 2 homolog

  • actin-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00230 ACTR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21472 Actr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27990 Actr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Actr2 NCBI NCBI:10097