ACTR2 - actin related protein 2 Gene

Also Known as ARP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10097

About ACTR2

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:65,227,831-65,271,253 (from NCBI)

This gene has 4 transcripts (splice variants), 260 orthologues and 26 paralogues. Ubiquitous expression in appendix (RPKM 135.1), lymph node (RPKM 134.7) and 25 other tissues.

Summary

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ACTR2 Products (2)

mRNA Protein Name
NM_001005386.3 NP_001005386.1 actin-related protein 2 isoform a
NM_005722.4 NP_005713.1 actin-related protein 2 isoform b

ACTR2 Protein Structure

Actin

Actin: Actin (5 - 388)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
Protein Preferred Names Protein Names

actin-related protein 2

  • ARP2 actin related protein 2 homolog

ACTR2 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82980 Actin Related Protein 2 Antibody (YA2725) WB, ICC/IF Human, Mouse, Rat
HY-P82980A Actin Related Protein 2 Antibody (YA2725)(PBS only) WB, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Wiskott-Aldrich Syndrome

  • WAS

  • Eczema-Thrombocytopenia-Immunodeficiency Syndrome

  • Immunodeficiency 2

  • Aldrich Syndrome

  • Imd2

  • Wiskott-Aldrich Syndrome 1

  • Was1

  • Wiskott Syndrome

  • Wiskott Aldrich Syndrome

  • Eczema Thrombocytopenia Immunodeficiency Syndrome

  • Imd 2
Myopathy, Centronuclear, 2

  • Myopathy, Centronuclear, Autosomal Recessive

  • Autosomal Recessive Centronuclear Myopathy

  • CNM2

  • Centronuclear Myopathy 2

  • Ar-Cnm

  • Myotubular Myopathy, Autosomal Recessive

  • Autosomal Recessive Myotubular Myopathy

  • Centronuclear Myopathy Autosomal Recessive

  • Myopathy, Centronuclear, Type 2
Coronin-1a Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00230 ACTR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21472 Actr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27990 Actr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ACTR2 MGD MGI:1913963
Canis familiaris ACTR2 VGNC VGNC:37554
Macaca mulatta ACTR2 VGNC VGNC:103782
Bos taurus ACTR2 VGNC VGNC:25586
Rattus norvegicus ACTR2 RGD RGD:1310826
Felis catus ACTR2 VGNC VGNC:59556
Others ACTR2 NCBI