Lsm14a - LSM14A mRNA processing body assembly factor Gene

Also Known as Tral; mRAP55A; 2700023B17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67070

Summary

Enables double-stranded DNA binding activity; double-stranded RNA binding activity; and single-stranded RNA binding activity. Acts upstream of or within RIG-I signaling pathway and positive regulation of type I interferon-mediated signaling pathway. Located in P-body. Is expressed in several structures, including gonad. Orthologous to human LSM14A (LSM14A mRNA processing body assembly factor). [provided by Alliance of Genome Resources, Apr 2022]

Lsm14a Products (4)

mRNA Protein Name
NM_001360654.1 NP_001347583.1 protein LSM14 homolog A isoform 2
NM_001360655.1 NP_001347584.1 protein LSM14 homolog A isoform 3
NM_001360656.1 NP_001347585.1 protein LSM14 homolog A isoform 4
NM_025948.3 NP_080224.1 protein LSM14 homolog A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
22745163 MGI
enables double-stranded RNA binding IDA
IDA: Inferred from direct assay
22745163 MGI
enables single-stranded RNA binding IDA
IDA: Inferred from direct assay
22745163 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within RIG-I signaling pathway IGI
IGI: Inferred from genetic interaction
22745163 MGI
acts upstream of or within defense response to virus IMP
IMP: Inferred from mutant phenotype
22745163 MGI
acts upstream of or within positive regulation of type I interferon-mediated signaling pathway IDA
IDA: Inferred from direct assay
22745163 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
22745163 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
20014101 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein LSM14 homolog A

  • LSM14 homolog A

  • RNA-associated protein 55A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160222 HSV-60mer sodium 98.11% Unkown
HY-RS07856 LSM14A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lsm14a NCBI NCBI:26065