Calcoco1 - calcium binding and coiled coil domain 1 Gene

Mus musculus

Also known as Cocoa; Gcap11; mKIAA1536; 1810009B06Rik

Gene ID: 67488 | Gene type: protein coding

About Calcoco1

Summary

Enables chromatin binding activity and transcription coactivator activity. Involved in intracellular steroid hormone receptor signaling pathway and positive regulation of transcription by RNA polymerase II. Located in chromatin. Is expressed in embryo and thymus primordium. Orthologous to human CALCOCO1 (calcium binding and coiled-coil domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Calcoco1 Products(1)

mRNA	Protein	Name
NM_026192.3	NP_080468.1	calcium-binding and coiled-coil domain-containing protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	15383530	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	14690606	MGI
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	14690606	MGI
enables transcription coactivator activity	IMP IMP: Inferred from mutant phenotype	24245781	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in nuclear receptor-mediated steroid hormone signaling pathway	IDA IDA: Inferred from direct assay	14690606	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14690606	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	15383530	MGI
involved in signal transduction	IDA IDA: Inferred from direct assay	14690606	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromatin	IDA IDA: Inferred from direct assay	15383530	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

calcium-binding and coiled-coil domain-containing protein 1

GRIP1-interacting protein	coiled-coil coactivator protein
coiled-coil transcriptional coactivator	granule cell antiserum positive 11

Calcoco1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Calcoco1	Q8CGU1	Bcat	Gallus gallus	O42486	Pull Down	16344550
Cross	Calcoco1	Q8CGU1	Bcat	Gallus gallus	O42486	Anti Bait CoIP	16344550

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01830	CALCOCO1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Calcoco1	NCBI	NCBI:57658

Name
Email *

	Sorry, but the email address you supplied was invalid.