2. Gene
  3. Prame - PRAME nuclear receptor transcriptional regulator Gene

Prame - PRAME nuclear receptor transcriptional regulator Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 680000 | Gene type: protein coding

About Prame

Summary

Predicted to enable retinoic acid receptor binding activity and ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of retinoic acid receptor signaling pathway; and negative regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of Cul2-RING ubiquitin Ligase complex. Predicted to be active in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human PRAME (PRAME nuclear receptor transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]

Prame Products(1)

mRNA Protein Name
XM_001055257.6 XP_001055257.2 melanoma antigen preferentially expressed in tumors
Protein Preferred Names Protein Names

PRAME nuclear receptor transcriptional regulator

melanoma antigen preferentially expressed in tumors

preferentially expressed antigen in melanoma

rCG38045-like

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990717 Brenetafusp Inhibitor 99.70% Phase 3
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P11280A PRAME peptide (425-433) acetate Degrader 98.16% Unkown
HY-RS11049 PRAME Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P992293 Anti-PRAME Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prame NCBI NCBI:23532