Prame - PRAME nuclear receptor transcriptional regulator Gene
Species: Rattus norvegicus
Summary
Predicted to enable retinoic acid receptor binding activity and ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of retinoic acid receptor signaling pathway; and negative regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of Cul2-RING ubiquitin Ligase complex. Predicted to be active in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human PRAME (PRAME nuclear receptor transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]
Prame Products (1)
| mRNA | Protein | Name |
|---|---|---|
| XM_001055257.6 | XP_001055257.2 | melanoma antigen preferentially expressed in tumors |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PRAME nuclear receptor transcriptional regulator melanoma antigen preferentially expressed in tumors |
|
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Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P11280A | PRAME peptide (425-433) acetate | Degrader | 98.16% | Unkown |
| HY-RS11049 | PRAME Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990717 | Brenetafusp | Inhibitor | 99.70% | Unkown |
| HY-P992293 | Anti-PRAME Antibody | / | Unkown |
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