Crtc1 - CREB regulated transcription coactivator 1 Gene

Also Known as Mect1; TORC1; TORC-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 684527

Summary

Predicted to enable cAMP response element binding protein binding activity. Involved in positive regulation of dendrite development; positive regulation of long-term synaptic potentiation; and postsynapse to nucleus signaling pathway. Located in cytoplasm; neuronal cell body; and nucleus. Is active in glutamatergic synapse and postsynaptic density. Colocalizes with dendrite and synapse. Biomarker of middle cerebral artery infarction. Orthologous to human CRTC1 (CREB regulated transcription coactivator 1). [provided by Alliance of Genome Resources, Apr 2022]

Crtc1 Products (1)

mRNA Protein Name
NM_001047115.2 NP_001040580.1 CREB-regulated transcription coactivator 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of dendrite development IMP
IMP: Inferred from mutant phenotype
21895802 RGD
involved in positive regulation of long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
17183642 RGD
involved in postsynapse to nucleus signaling pathway EXP
EXP: Inferred from Experiment
22770221 RGD
involved in postsynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
22770221 RGD
involved in postsynapse to nucleus signaling pathway IEP
IEP: Inferred from expression pattern
22770221 RGD
involved in postsynapse to nucleus signaling pathway IMP
IMP: Inferred from mutant phenotype
22770221 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
22770221 RGD
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
22770221 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22770221 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22770221 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
22770221 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
22770221 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CREB-regulated transcription coactivator 1

  • mucoepidermoid carcinoma translocated 1

  • mucoepidermoid carcinoma translocated protein 1 homolog

  • transducer of CREB protein 1

  • transducer of regulated cAMP response element-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0059 D-Arabinose ≥99.0% Unkown
HY-N7082 D-Arabinopyranose 99.94% Unkown
HY-N0059R D-Arabinose (Standard) / Unkown
HY-N0059S D-Arabinose-13C / Unkown
HY-N0059S1 D-Arabinose-13C-1 / Unkown
HY-N0059S2 D-arabinose-13C-2 / Unkown
HY-N0059S3 D-Arabinose-13C-3 / Unkown
HY-N0059S4 D-Arabinose-d2 / Unkown
HY-N0059S5 D-Arabinose-d5 / Unkown
HY-N0059S6 D-Arabinose-d6 / Unkown
HY-N7082S D-Arabinopyranose-13C5 99.9% Unkown
HY-RS03200 CRTC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22459 Crtc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crtc1 NCBI NCBI:23373