FPGS - Fpgs folylpolyglutamate synthase Gene

Rattus norvegicus

Gene ID: 687266 | Gene type: protein coding

About FPGS

Summary

Enables tetrahydrofolylpolyglutamate synthase activity. Involved in animal organ regeneration; brain development; and liver development. Predicted to be active in cytosol and mitochondrion. Orthologous to human FPGS (folylpolyglutamate synthase). [provided by Alliance of Genome Resources, Apr 2022]

FPGS Products(1)

mRNA	Protein	Name
NM_001146125.2	NP_001139597.2	folylpolyglutamate synthase, mitochondrial precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables tetrahydrofolylpolyglutamate synthase activity	IDA IDA: Inferred from direct assay	6892914	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in animal organ regeneration	IEP IEP: Inferred from expression pattern	3654111	RGD
involved in liver development	IEP IEP: Inferred from expression pattern	1435744	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

folylpolyglutamate synthase, mitochondrial

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14945	Remogliflozin etabonate	Inhibitor	99.64%	Phase 2

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W018158	DHICA		96.91%	Unkown
HY-79139	Pteroic acid		98.05%	Unkown
HY-W018158R	DHICA (Standard)		95.20%	Unkown
HY-113798	ICI 198583		/	Unkown
HY-125316	AMG-151		/	Unkown
HY-D1199	Blue FPG-A trisodium	Antagonist	/	Unkown
HY-RS05083	FPGS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-122259	AMPte-Glu-γ-Glu	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	FPGS	NCBI	NCBI:2356

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