FPGS - Fpgs folylpolyglutamate synthase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 687266

Summary

Enables tetrahydrofolylpolyglutamate synthase activity. Involved in animal organ regeneration; brain development; and liver development. Predicted to be active in cytosol and mitochondrion. Orthologous to human FPGS (folylpolyglutamate synthase). [provided by Alliance of Genome Resources, Apr 2022]

FPGS Products (1)

mRNA Protein Name
NM_001146125.2 NP_001139597.2 folylpolyglutamate synthase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables tetrahydrofolylpolyglutamate synthase activity IDA
IDA: Inferred from direct assay
6892914 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
3654111 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
1435744 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

folylpolyglutamate synthase, mitochondrial

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-14945 Remogliflozin etabonate Inhibitor 99.64% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W018158 DHICA 96.91% Unkown
HY-79139 Pteroic acid 98.05% Unkown
HY-W018158R DHICA (Standard) 95.20% Unkown
HY-113798 ICI 198583 / Unkown
HY-125316 AMG-151 / Unkown
HY-D1199 Blue FPG-A trisodium Antagonist / Unkown
HY-RS05083 FPGS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-122259 AMPte-Glu-γ-Glu Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FPGS NCBI NCBI:2356