Klhdc2 - kelch domain containing 2 Gene

Also Known as LCP; HCLP-1; D12Ertd522e; 2310022K15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69554

Summary

Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in nuclear body and nuclear membrane. Predicted to be part of Cul2-RING ubiquitin Ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human KLHDC2 (kelch domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Klhdc2 Products (1)

mRNA Protein Name
NM_027117.3 NP_081393.2 kelch domain-containing protein 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kelch domain-containing protein 2

  • endothelial differentiation inhibitory protein TNG

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-168536 SJ46411 / Unkown
HY-180280 KLHDC2 ligand 3 / Unkown
HY-180263 KLHDC2 ligand 4 / Unkown
HY-168535 SJ6145 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klhdc2 NCBI NCBI:23588