Vps36 - vacuolar protein sorting 36 Gene

Also Known as Eap45; 1700010A24Rik; 2210415M20Rik; 2810408E15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70160

Summary

Enables ubiquitin binding activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within endosomal transport. Located in late endosome and lysosome. Orthologous to human VPS36 (vacuolar protein sorting 36 homolog). [provided by Alliance of Genome Resources, Apr 2022]

Vps36 Products (2)

mRNA Protein Name
NM_001368379.1 NP_001355308.1 vacuolar protein-sorting-associated protein 36 isoform 2
NM_027338.2 NP_081614.1 vacuolar protein-sorting-associated protein 36 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ubiquitin binding IDA
IDA: Inferred from direct assay
15755741 MGI
Cellular Component GO Annotation Evidence References Source
located in late endosome IDA
IDA: Inferred from direct assay
15755741 MGI
located in lysosome IDA
IDA: Inferred from direct assay
15755741 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein-sorting-associated protein 36

  • ESCRT-II complex subunit VPS36

Vps36 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Vps36 Q91XD6 RPS27A Bos taurus P62990
SPR
17057714
Cross
Vps36 Q91XD6 RPS27A Bos taurus P62990
X-Ray Diffraction
17057714
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15687 VPS36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps36 NCBI NCBI:51028