Crtc3 - CREB regulated transcription coactivator 3 Gene

Also Known as TORC3; 2610312F20Rik; 6332415K15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70461

Summary

Predicted to enable cAMP response element binding protein binding activity. Involved in positive regulation of CREB transcription factor activity. Acts upstream of or within several processes, including energy homeostasis; negative regulation of adenylate cyclase-activating Adrenergic Receptor signaling pathway; and negative regulation of lipid catabolic process. Located in cytoplasm and nucleus. Orthologous to human CRTC3 (CREB regulated transcription coactivator 3). [provided by Alliance of Genome Resources, Apr 2022]

Crtc3 Products (1)

mRNA Protein Name
NM_173863.2 NP_776288.2 CREB-regulated transcription coactivator 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30611118 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within energy homeostasis IMP
IMP: Inferred from mutant phenotype
21164481 MGI
acts upstream of lipid catabolic process IMP
IMP: Inferred from mutant phenotype
21164481 MGI
acts upstream of or within negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway IDA
IDA: Inferred from direct assay
21164481 MGI
acts upstream of or within negative regulation of lipid catabolic process IMP
IMP: Inferred from mutant phenotype
21164481 MGI
involved in positive regulation of CREB transcription factor activity IMP
IMP: Inferred from mutant phenotype
30611118 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21164481 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21164481 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21164481 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CREB-regulated transcription coactivator 3

  • TORC-3

  • transducer of CREB protein 3

  • transducer of regulated cAMP response element-binding protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120877 MRT199665 99.85% Unkown
HY-120877A (R)-MRT199665 98.70% Unkown
HY-171591 SIK2-IN-4 Inhibitor 99.06% Unkown
HY-171590 SIK2-IN-3 Inhibitor / Unkown
HY-RS03202 CRTC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crtc3 NCBI NCBI:64784