RIOX1 - ribosomal oxygenase 1 Gene

Also Known as ROX; NO66; JMJD9; MAPJD; URLC2; hsNO66; C14orf169

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79697

Summary

Enables peptidyl-histidine dioxygenase activity and protein demethylase activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of osteoblast differentiation. Located in nucleolus. [provided by Alliance of Genome Resources, Jun 2026]

RIOX1 Products (1)

mRNA Protein Name
NM_024644.5 NP_078920.2 ribosomal oxygenase 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables 2-oxoglutarate-dependent dioxygenase activity IDA
IDA: Inferred from direct assay
35210392 GOA
enables peptidyl-histidine dioxygenase activity EXP
EXP: Inferred from Experiment
23103944 GOA
enables peptidyl-histidine dioxygenase activity IDA
IDA: Inferred from direct assay
23103944 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
19927124 GOA
enables protein demethylase activity IDA
IDA: Inferred from direct assay
35210392 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RIOX1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
RIOX1 Q9H6W3 Sp7 Mus musculus Q8VI67
Pull Down
19927124
Cross
RIOX1 Q9H6W3 Sp7 Mus musculus Q8VI67
Anti Tag CoIP
19927124
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12304 IOX1 Inhibitor 99.89% Unkown
HY-RS11988 RIOK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11991 RIOX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18840 Riok1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25332 Riok1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown