CHD9 - chromodomain helicase DNA binding protein 9 Gene

Homo sapiens

Also known as AD013; CHD-9; CReMM; KISH2; PRIC320

Gene ID: 80205 | Gene type: protein coding

About CHD9

Cytogenetic location: 16q12.2 Genomic coordinates (GRCh38): 16:53,054,991-53,327,497 (from NCBI)

This gene has 21 transcripts (splice variants), 218 orthologues and 30 paralogues. Ubiquitous expression in thyroid (RPKM 7.0), ovary (RPKM 6.1) and 25 other tissues.

Summary

Predicted to enable ATP binding activity; ATP-dependent activity, acting on DNA; and DNA binding activity. Predicted to be involved in DNA duplex unwinding and chromatin organization. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CHD9 Products(9)

mRNA	Protein	Name
NM_001308319.2	NP_001295248.1	chromodomain-helicase-DNA-binding protein 9 isoform 1
NM_001352127.3	NP_001339056.1	chromodomain-helicase-DNA-binding protein 9 isoform 2
NM_001352156.3	NP_001339085.1	chromodomain-helicase-DNA-binding protein 9 isoform 3
NM_001352157.3	NP_001339086.1	chromodomain-helicase-DNA-binding protein 9 isoform 4
NM_001352158.3	NP_001339087.1	chromodomain-helicase-DNA-binding protein 9 isoform 5
NM_001382353.1	NP_001369282.1	chromodomain-helicase-DNA-binding protein 9 isoform 1
NM_001382354.1	NP_001369283.1	chromodomain-helicase-DNA-binding protein 9 isoform 6
NM_001382355.1	NP_001369284.1	chromodomain-helicase-DNA-binding protein 9 isoform 7
NM_025134.7	NP_079410.4	chromodomain-helicase-DNA-binding protein 9 isoform 2

CHD9 Protein Structure

Chromo

SNF2_N

Helicase_C

BRK

0
500
1000
1500
2000
2500
2897 a.a.

Protein Preferred Names

Protein Names

chromodomain-helicase-DNA-binding protein 9

ATP-dependent helicase CHD9

Related Diseases

Diseases

Alias

Childhood Supratentorial Ependymoma

Paediatric Cerebral Ependymoma	Paediatric Supratentorial Ependymoblastoma
Paediatric Supratentorial Ependymoma	Pediatric Cerebral Ependymoma
Pediatric Supratentorial Ependymoblastoma	Pediatric Supratentorial Ependymoma

Charge Syndrome

Charge Association	Hall-Hittner Syndrome
Charge Association--Coloboma, Heart Anomaly, Choanal Atresia, Retardation, Genital And Ear Anomalies	Hhs
Coloboma, Heart Anomaly, Choanal Atresia, Restriction Of Growth And Development, Genital And Ear Anomalies	Coloboma-Heart Defects-Atresia Choanae-Retardation Of Growth And Development-Genitourinary Problems-Ear Abnormalities Syndrome
CHARGES

Choanal Atresia, Posterior

Choanal Atresia	Atresia Of Nares
Posterior Choanal Atresia	PCA
Imperforate Nares	Choanal Fusion
Congenital Stenosis Of Nares	Congenital Stenosis Of Choanae
Nasal Atresia Nos

Coloboma Of Macula

Coloboma	Congenital Ocular Coloboma
Microphthalmia, Isolated, With Coloboma	Agenesis Of Macula
Hereditary Macular Coloboma	Ocular Coloboma
Coloboma Of Eye	Macular Coloboma
Uveoretinal Coloboma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02614	CHD9 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CHD9	RGD	RGD:1306795
Bos taurus	CHD9	VGNC	VGNC:27284
Canis familiaris	CHD9	VGNC	VGNC:39207
Macaca mulatta	CHD9	VGNC	VGNC:71101
Mus musculus	CHD9	MGD	MGI:1924001