GDPD5 - glycerophosphodiester phosphodiesterase domain containing 5 Gene

Homo sapiens

Also known as GDE2; PP1665

Gene ID: 81544 | Gene type: protein coding

About GDPD5

Cytogenetic location: 11q13.4-q13.5 Genomic coordinates (GRCh38): 11:75,434,640-75,525,941 (from NCBI)

This gene has 17 transcripts (splice variants), 274 orthologues and 5 paralogues. Broad expression in spleen (RPKM 16.9), fat (RPKM 8.6) and 14 other tissues.

Summary

Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]

GDPD5 Products(3)

mRNA	Protein	Name
NM_001351167.2	NP_001338096.1	glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 2
NM_001351168.1	NP_001338097.1	glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 3
NM_030792.8	NP_110419.5	glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 1

GDPD5 Protein Structure

GDPD

0
100
200
300
400
500
605 a.a.

Protein Preferred Names

Protein Names

glycerophosphodiester phosphodiesterase domain-containing protein 5

glycerophosphocholine phosphodiesterase GDPD5

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder, Autosomal Dominant 41

MRD41	Autosomal Dominant Non-Syndromic Intellectual Disability 41
Mental Retardation, Autosomal Dominant 41	Autosomal Dominant Intellectual Developmental Disorder 41
Autosomal Dominant Mental Retardation 41	Mental Retardation, Autosomal Dominant, Type 41

Coffin-Siris Syndrome 1

Coffin-Siris Syndrome	Fifth Digit Syndrome
Css	CSS1
Mrd12	Mental Retardation, Autosomal Dominant 12
Hhid	Dwarfism-Onychodysplasia
Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features	Autosomal Dominant Mental Retardation 12
Short Stature-Onychodysplasia.	Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx
Mental Retardation With Hypoplastic Fifth Fingernails And Toenails	Short Stature-Onychodysplasia
Coffin-Siris Syndrome, Type 1	Mental Retardation, Autosomal Dominant, Type 12

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05365	GDPD5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GDPD5	RGD	RGD:1559673
Felis catus	GDPD5	VGNC	VGNC:62511
Macaca mulatta	GDPD5	VGNC	VGNC:72801
Canis familiaris	GDPD5	VGNC	VGNC:41170
Bos taurus	GDPD5	VGNC	VGNC:29313
Mus musculus	GDPD5	MGD	MGI:2686926

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