UTP15 - UTP15 small subunit processome component Gene

Homo sapiens

Also known as NET21

Gene ID: 84135 | Gene type: protein coding

About UTP15

Cytogenetic location: 5q13.2 Genomic coordinates (GRCh38): 5:73,565,741-73,583,380 (from NCBI)

This gene has 8 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in bone marrow (RPKM 3.2), thyroid (RPKM 2.7) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in endoplasmic reticulum and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

UTP15 Products(3)

mRNA	Protein	Name
NM_001284430.1	NP_001271359.1	U3 small nucleolar RNA-associated protein 15 homolog isoform 2
NM_001284431.1	NP_001271360.1	U3 small nucleolar RNA-associated protein 15 homolog isoform 3
NM_032175.4	NP_115551.2	U3 small nucleolar RNA-associated protein 15 homolog isoform 1

UTP15 Protein Structure

WD40

UTP15_C

0
100
200
300
400
518 a.a.

Protein Preferred Names

Protein Names

U3 small nucleolar RNA-associated protein 15 homolog

Src-associated protein SAW

Related Diseases

Diseases

Alias

Branchiooculofacial Syndrome

Branchio-Oculo-Facial Syndrome	BOFS
Bof Syndrome	Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome
Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome	Branchial Clefts With Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, And Premature Aging
Branchial Clefts With Characteristic Facies Growth Retardation Imperforate Nasolacrimal Duct And Premature Aging	Bofs Syndrome
Lip Pseudocleft-Hemagiomatous Branchial Cyst Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-107372S4	Uridine triphosphate-15N2 dilithium		/	Unkown
HY-RS15576	UTP15 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	UTP15	VGNC	VGNC:79539
Canis familiaris	UTP15	VGNC	VGNC:48209
Rattus norvegicus	UTP15	RGD	RGD:1310992
Bos taurus	UTP15	VGNC	VGNC:36742
Mus musculus	UTP15	MGD	MGI:2145443
Felis catus	UTP15	VGNC	VGNC:66902

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