Asah1 - N-acylsphingosine amidohydrolase 1 Gene

Also Known as Asah

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84431

Summary

Predicted to enable N-acylsphingosine amidohydrolase activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in lung development and response to organic substance. Predicted to be located in extracellular space; lysosome; and nucleus. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Asah1 Products (1)

mRNA Protein Name
NM_053407.3 NP_445859.2 acid ceramidase precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in lung development IDA
IDA: Inferred from direct assay
9160843 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acid ceramidase

  • AC

  • ACDase

  • N-acylethanolamine hydrolase ASAH1

  • N-acylsphingosine amidohydrolase (acid ceramidase) 1

  • acid CDase

  • acylsphingosine deacylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141866 Acid Ceramidase-IN-1 Inhibitor 99.36% Unkown
HY-158783 SACLAC 99.70% Unkown
HY-RS01053 ASAH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18163 Asah1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24637 Asah1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asah1 NCBI NCBI:427