AP5B1 - adaptor related protein complex 5 subunit beta 1 Gene

Also Known as AP-5; PP1030

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 91056

Summary

Involved in endosomal transport. Located in lysosomal membrane. Part of AP-type membrane coat adaptor complex. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in bone marrow (RPKM 18.6), spleen (RPKM 4.9) and 24 other tissues.

AP5B1 Products (1)

mRNA Protein Name
NM_138368.5 NP_612377.4 AP-5 complex subunit beta-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20613862 GOA
Biological Process GO Annotation Evidence References Source
involved in endosomal transport IMP
IMP: Inferred from mutant phenotype
22022230 GOA
Cellular Component GO Annotation Evidence References Source
part of AP-type membrane coat adaptor complex IDA
IDA: Inferred from direct assay
22022230 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AP5B1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
AP5B1 Q2VPB7 CAMK2B Homo sapiens Q13554
Anti Tag CoIP
33961781
Intra
AP5B1 Q2VPB7 CAMK2B Homo sapiens Q13554
Y2H Prey Pooling
25416956
Intra
AP5B1 Q2VPB7 NIF3L1 Homo sapiens Q9GZT8
Y2H Prey Pooling
25416956
Intra
AP5B1 Q2VPB7 NIF3L1 Homo sapiens Q9GZT8
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100166 AP521 Agonist 99.31% Unkown
HY-105161 AP-521 free base Agonist / Unkown
HY-RS00776 AP1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00786 AP2B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00789 AP3B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00796 AP4B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00800 AP5Z1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00804 APBB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown