OPALIN - oligodendrocytic myelin paranodal and inner loop protein Gene

Homo sapiens

Also known as TMP10; HTMP10; TMEM10

Gene ID: 93377 | Gene type: protein coding

About OPALIN

Cytogenetic location: 10q24.1 Genomic coordinates (GRCh38): 10:96,343,221-96,359,002 (from NCBI)

This gene has 6 transcripts (splice variants) and 91 orthologues. Restricted expression toward brain (RPKM 29.7).

Summary

Predicted to be involved in regulation of oligodendrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

OPALIN Products(10)

mRNA	Protein	Name
NM_001040102.3	NP_001035191.1	opalin isoform b
NM_001040103.3	NP_001035192.1	opalin isoform c
NM_001284320.2	NP_001271249.1	opalin isoform d
NM_001284321.2	NP_001271250.1	opalin isoform e
NM_001284322.2	NP_001271251.1	opalin isoform c
NM_001284323.2	NP_001271252.1	opalin isoform c
NM_001284324.2	NP_001271253.1	opalin isoform c
NM_001284326.2	NP_001271255.1	opalin isoform f
NM_001284327.2	NP_001271256.1	opalin isoform f
NM_033207.5	NP_149984.1	opalin isoform a

Protein Preferred Names

Protein Names

opalin

transmembrane protein 10

Recombinant OPALIN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77113	OPALIN Protein, Human (HEK293, Fc)	Q96PE5 (T51-E141)	≥95%

Related Diseases

Diseases

Alias

Fucosidosis

Alpha-L-Fucosidase Deficiency	Fucosidase Deficiency Disease
A-Fucosidase Deficiency	Alpha Fucosidase Deficiency
Lysosomal Storage Disease Caused By Defective Alpha-L-Fucosidase With Accumulation Of Fucose In The Tissues	Alpha-Fucosidase Deficiency
Fucosidase Deficiency	FUCA1D

Multiple Sclerosis

MS	Multiple Sclerosis, Susceptibility To
Disseminated Sclerosis	Multiple Sclerosis, Disease Progression, Modifier Of
Insular Sclerosis	Multiple Sclerosis Modifier Of Disease Progression
Multiple Sclerosis, Susceptibility To 1	Multiple Sclerosis, Susceptibility To, 1
Multiple Sclerosis 1	Generalized Multiple Sclerosis
Multiple Sclerosis Variant	Multiple Sclerosis Susceptibility To
Cerebrospinal Sclerosis	Generalised Multiple Sclerosis
Ms - [Multiple Sclerosis]	Disseminated Cerebrospinal Sclerosis
Disseminated Multiple Sclerosis	Disseminated Nervous System Myelosclerosis
Multiple Cerebrospinal Sclerosis	Multiple Combined Sclerosis
Multiple Sclerosis Generalised	Disseminated Brain Sclerosis
Disseminated Spinal Sclerosis	Insular Brain Sclerosis
Miliary Brain Sclerosis	Multiple Combined Sclerosis Of Spinal Cord
Multiple Ascending Sclerosis	Multiple Brain Sclerosis
Multiple Sclerosis Of Brain Stem	Multiple Sclerosis Of The Brain Stem
Multiple Sclerosis Of Cord	Sclérose En Plaques
Plaque Sclerosis	Multiple Sclerosis Of The Spinal Cord

Pelizaeus-Merzbacher Disease

PMD	HLD1
Pelizaeus-Merzbacher Brain Sclerosis	Leukodystrophy, Hypomyelinating, 1
Diffuse Familial Brain Sclerosis	Pelizaeus Merzbacher Brain Sclerosis
Sudanophilic Leukodystrophy, Paelizeus-Merzbacher Type	Cockayne-Pelizaeus-Merzbacher Disease
Hypomyelinating Leukodystrophy 1	Leukodystrophy, Sudanophilic
Pelizaeus Merzbacher Disease	Hypomyelinating Leukodystrophy, 1
Sudanophilic Leukodystrophy	Pelizaeus-Merzbacher Disease, Connatal Form
Connatal Pmd	Pelizaeus-Merzbacher Disease Type Ii
Severe Pmd	Null Syndrome
Plp1 Null Syndrome	Pelizaeus-Merzbacher Disease, Null Syndrome
Brain Sclerosis Diffuse Familial	Sudanophilic Leukodystrophy Paelizeus-Merzbacher Type
Leukodystrophy Hypomyelinating 1	Diffuse Cerebral Sclerosis Of Schilder

Hypomyelinating Leukodystrophy

Hld	Leukodystrophy, Hypomyelinating

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09791	OPALIN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	OPALIN	VGNC	VGNC:44127
Bos taurus	OPALIN	VGNC	VGNC:32434
Rattus norvegicus	OPALIN	RGD	RGD:1307776
Macaca mulatta	OPALIN	VGNC	VGNC:75443
Mus musculus	OPALIN	MGD	MGI:2657025

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