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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
2-Hydroxypropanamide
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "2-Hydroxypropanamide" in MCE Product Catalog:
16
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
1
1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
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1
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Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide is the drug-linker conjugate for ADC, containing ADC linker Gly-Mal-GGFG and ADC cytotoxin Deruxtecan 2-hydroxypropanamide .
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Deruxtecan 2-hydroxypropanamide is a highly stable Deruxtecan (HY-13631E) analog that specifically binds to receptors highly expressed in tumor cells .
Cat. No.: HY-164702
Synonyms: Izalontamab Brengitecan
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BL-B01D1 (Izalontamab Brengitecan) is a bispecific antibody-drug conjugate (ADC) targeting EGFR and HER3, formed by conjugating the EGFR/HER3 bispecific antibody Izalontamab (HY-P99676) to a novel TOP-I inhibitor payload Deruxtecan 2-hydroxypropanamide (HY-153891) via a cleavable linker (Mc-Gly-Gly-Phe-Gly). BL-B01D1 binds to EGFR and HER3 on the surface of tumor cells, mediates endocytosis and releases the payload, inhibits topoisomerase I, blocks DNA replication and RNA synthesis, and disrupts DNA structure. BL-B01D1 induces cell cycle S-phase arrest, apoptosis, antibody-dependent cell-mediated cytotoxicity, and tumor cell death. BL-B01D1 can be used for cancer research [2] .
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
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Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Cat. No.: HY-153891S
Cat. No.: HY-P3100
CAS No.: 939960-34-6
Cat. No.: HY-125357
CAS No.: 148619-41-4
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Cat. No.: HY-158104
Cat. No.: HY-P11293
CAS No.: 1309855-53-5
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
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Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
